【作者】 蔡明建；

【导师】 朱迪；

【作者基本信息】 湖南中医药大学 ， 中医内科学， 2012， 硕士

【摘要】 目的：探讨加味仙桔汤治疗脾虚湿热型慢性腹泻的临床疗效和安全性。方法：选择2011年4月至2012年2月门诊治疗的60例脾虚湿热型慢性腹泻患者。采用随机的原则分为两组,即治疗组和对照组,分别给予加味仙桔汤和肠康片治疗4周,实验结束后分别进行治疗前后中医证候疗效和积分观察,对比两组的中医症候及主症变化,并对止泻起效时间和止痛起效时间进行比较。结果：加味仙桔汤治疗组总有效率为92.86%,对照组总有效率为79.31%,有显著统计学差异(p<0.05),提示加味仙桔汤组在改善慢性腹泻中医证候疗效方面优于对照组。治疗4周后疗效差异具有显著统计学意义(p<0.05),提示加味仙桔汤组在改善中医证候方面较对照组有优势。两组止泻和止痛起效时间相比均有显著统计学差异(P<0.01),提示加味仙桔汤组在改善慢性腹泻的泄泻、腹痛症状方面较对照组有优势。治疗过程中未见明显不良反应。结论：加味仙桔汤是临床治疗脾虚湿热型慢性腹泻安全、有效的方药。更多还原

【Abstract】 Objective:To observe the clinical effects of Jia Wei Xian Jie Tang on patients with chronic diarrhea.Methods:60cases of patients with chronic diarrhea (spleen deficiency and liquid stagnation syndrome) from April2011to February2012were selected and divided into two groups randomly (treatment group and control group), and treated with Jia Wei Xian Jie Tang and Chang Kang tablets respectively for four weeks. The curative effect on Chinese medical syndromes, anti-diarrheal onset time and analgesic onset time were observed.Results:The total effective rate of Chinese medical syndromes was92.86%in the treatment group and79.31%in the control group,with a significant difference between the two groups (P<0.05). After tour weeks, significant difference between the two groups of symptom integral comparison was found (P<0.05).There was significant difference between the two groups in anti-diarrheal onset time and analgesic onset time (P<0.01). No side effects showed during the course of treatment.Conclusions:Jia Wei Xian Jie Tang is a safe and effective prescription to the patient with chronic diarrhea.更多还原