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糖尿病结肠传输异常的发生率及相关因素分析

Diabetic Colonic Motility Disorders and Related Factors

【作者】 曹京梅

【导师】 魏良洲;

【作者基本信息】 青岛大学 , 内科学, 2012, 硕士

【摘要】 目的1.验证不透X线标记物在临床诊断结肠慢传输的作用。2.研究2型糖尿病(DM)患者的结肠传输异常的发生情况及相关的影响因素。方法以152例DM患者,健康志愿者30例为研究对象,其中48hGITT检测异常合并消化道症状DM患者33例设分为观察组1、31例48hGITT检测异常无消化道症状患者为观察组2,并以88例48hGITT检测正常无消化道症状DM患者为对照组,对三组别进行多因素分析。结果152例DM患者结肠传输异常发生率为42.1%,三组平均病程、FPG、SBP、SDP观察组1与其他两组均存在统计学差异,HbAlc三组别两两比较均有统计学差异。结论长期的血糖、血压控制不良会加速DM患者结肠功能紊乱并发症的发生。

【Abstract】 Objective1.To prove the role of radioopaque markers in the evaluation of colonic transit function.2. To study of type2diabetes mellitus (DM) patients with colonic transmission abnormality occurrence and related factors.Methods152cases of patients with DM and30cases of healthy volunteers as the research object, wherein48hGITT detection of abnormalities associated with gastrointestinal symptoms of33patients with DM have divided into the observation group1,31cases of48hGITT detection of abnormal gastrointestinal symptoms patients into the observation group2, and8848hGITT detection of normal gastrointestinal symptoms in DM patients as a control group, three groups of multiple factors analysis.Result The152cases of DM patients with abnormal colonic transit rate was42.1%, the average duration of three groups, FPG and SBP, the SDP observation group and the other two groups there was significant difference of HbAlc three groups were statistically significant pairwise comparisons between.Conclusion long-term glucose, poor control of blood pressure can accelerate DM patients with colonic dysfunction complications.

  • 【网络出版投稿人】 青岛大学
  • 【网络出版年期】2012年 10期
  • 【分类号】R587.1
  • 【下载频次】13
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