【作者】 钟鸣；

【导师】 郑靖；

【作者基本信息】 西南交通大学 ， 机械工程， 2011， 硕士

【摘要】 鉴于车祸、外伤和老龄化社会的日益加剧,国内外需要进行关节置换的患者越来越多,并且呈现年轻化趋势。人工关节植入人体后,可能会由于与骨界面整合不佳导致植入体-骨界面微动松动,进而引发植入体失效。此外,在具有生命组织参与的摩擦界面中,由于环境腐蚀行为与生物学反应的存在,其摩擦磨损的内涵与过程将比传统摩擦变得更为复杂。因此,有必要深入开展骨及其植入体的摩擦学行为与机理的研究,探讨骨-植入体界面获得良好稳定性结合的临界条件,为新型防松动植入体的摩擦学设计提供理论依据。本文在可控气氛卧式往复滑动摩擦磨损试验机上,采用球—平面接触模式,对人股骨皮质骨纵剖面在林格氏液和空气介质中的切向微动摩擦磨损行为进行了体外模拟试验。使用扫描电子显微镜(SEM)、激光共聚焦扫描显微镜(LCEM)、双模式轮廓仪(Nanomap 500DLS)、光学显微镜(OM)等表面分析测试设备,初步探索了人股骨皮质骨纵剖面的切向微动磨损机制。本文取得的主要结果如下：1、在林格氏液介质工况下,在10000次循环之前,随着循环次数增加,人股骨皮质骨纵剖面的摩擦系数呈现波动,但未出现显著增大趋势；10000次循环之后,随着循环次数增加,皮质骨表面的摩擦系数显著增大。2、随着循环次数增加,人股骨皮质骨纵剖面的磨损宽度与深度均显著增大,磨损形貌从明显的犁削效应逐渐转变为大块剥落。3、人股骨皮质骨纵剖面在林格氏液介质和干摩擦两种工况下呈现出相似的磨损机制,其中,干摩擦工况下人股骨皮质骨纵剖面磨损表面的磨屑较多。更多还原

【Abstract】 With traffic accidents, traumas, and aging society coming, there are more and more people needing to receive joint replacement treatments, moreover, which proves a lower -age tendency. After the joint replacement surgery, poor osseointegration of bone-implant interface could result in the fretting loosening. Furthermore, body fluid plays an important role in the tribological behaviors of joint friction pairs, which would cause those friction and wear process more complex in comparison with engineering friction pairs. Understanding the tribological behaviors of human bone and joint prostheses would help design new artificial joint with excellent resistance against lessening.The tangential fretting friction and wear behaviors of human femur cortical bone have been tested under ball-on-flat contact using a reciprocating apparatus. All the tests were conducted under dry condition and under the lubrication of Ringer’s solution. Various analyses by using microhardness tester, profilometer, optical microscopy, laser confocal scanning microscopy (LCSM), and scanning electron microscopy (SEM), have been performed. Main conclusions are drawn as follows:1. Under the lubrication of Ringer’s solution, the friction coefficient of cortical bone fluctuated but did not increase obviously before 10 000 cycles as the number of cycles increased. After 10 000 cycles, the friction coefficient of cortical bone increases significantly with the number of cycles.3. The wear width and depth of cortical bone increased with the number of cycles under the lubrication of Ringer’s solution. Moreover, the wear morphology changed gradually from significantly ploughing effect into bulk delamination.4. The cortical bone exhibited similar wear mechanism under the lubrication of Ringer’s solution and under dry condition. More wear particles were observed on the worn surface of cortical bone under the dry condition than under the lubrication of Ringer’s solution.更多还原