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电项针治疗抑郁症临床研究

Clinical Study of the Electro-Nape Acupuncture in the Treatment of Depression

【作者】 周磊

【导师】 高维滨;

【作者基本信息】 黑龙江中医药大学 , 针灸推拿学, 2011, 硕士

【摘要】 抑郁症是临床常见病,严重影响了患者的生活质量。近年来随着生活节奏变快,压力增加,抑郁症的发病率逐年上升。因而,对抑郁症的治疗日显重要。而西医在药物治疗过程中,许多药物的副作用,例如失眠、恶心、口干等,严重影响患者的使用及疗效,传统中医治疗抑郁症疗效显著,尤其是针灸疗法报道较多,现在已经开始进行机理研究。本课题从电项针疗法研究入手,将为治疗抑郁症提供新的治疗方法。目的:观察电项针治疗抑郁症的临床疗效,并与口服左洛复进行疗效比较。方法:将符合第3版《中国精神障碍分类与诊断标准》和《抑郁症:中西医基础与临床》2006年第一版诊断标准的70例患者随机分为对照组(A左洛复组)、治疗组(B电项针组),治疗前和治疗1个疗程(6周)后分别按照Davis JM的HAMD划界分,中医症候积分和SDS进行评分结果:(1).HAMD减分疗效做标准进行比较,两组组内治疗后均优于治疗前,差异显著(p<0,05),组间治疗前后总减分差值无显著差别(p>0.05);以HAMD有效率做标准进行比较,治疗组总有效率优于对照组,差别显著(p<0.05)(2).以中医症状减分疗效为标准进行比较,两组内治疗后优于治疗前,差别显著(p<0.05);两组间治疗前后总减分差值比较治疗组优于对照组,有显著差别(p<0.05);以中医症候有效率做标准进行比较治疗组总有效率优于对照组,差异显著(p<0.05)(3).以SDS评分疗效做标准进行比较,两组内治疗后均优于治疗前,差别显著(p<0.05);两组间治疗前后总减分差值有显著差别(p<0.05)治疗组优于对照组。结论:1.电项针疗法治疗抑郁症疗效显著。2.电项针治疗抑郁症效果优于左洛复(有效成分舍曲林辉瑞公司研制),且副作用小可操作性强。

【Abstract】 As a familiar disease, Depression serious impact the quality of life of the patient. With the rhythm of life being more faster, the morbidity of the Depression are enhancing.So caring this disease become more and more important. But western medicine use Pharmacotherapy in Depress to control depressive mood and alleviate symptoms. But the side-effects of anti-depression medicine is numerous, for example insomnia nausea, mouth dry. These side-effects could aggravate the state of depression and affect curative effect. However the traditional Chinese medicine has its predominance in treatment of depression especially using acupuncture. This task offers a method in care Depression using electro-nape acupunctureObjective:To investigate the clinical therapeutic effect of electro-nape acupuncture on depression.Methods:A random group trial was designed. Patients meeting the including criteria were randomly allocated to two groups. The treatment group was treated with electro-nape acupuncture once daily,6 weeks as a course and the control group, with Sertraline HCL Tablets,6weeks as a course. The HAMD and SRD Depression Scale were used to score before and after treatment for the evaluation of the therapeutic effects.Results:After one course of treatment, we find:(1)Two groups have more significant difference in reducing HAMD scores, before and after treatment(P<0.05)respectively; but comparison between the two groups showed insignificant difference (P>0.05). In efficiency, comparison between the two groups showed the treatment group better than the control group and nave significant difference (P<0.05).(2) The two groups before and after treatment by Traditional Chinese Medicine symptoms scores and efficiency have more significant differences(P<0.05); comparison between the two groups showed that the treatment group better than the control group and have significant differences (P<0.05).(3) The two groups before and after treatment by SDS scores have more significant differences(P<0.05); comparison between the two groups showed that the treatment group better than the control group and have significant differences (P<0.05).Conclusion:Acupuncture has a satisfactory therapeutic effect on depression.

【关键词】 抑郁症电项针左洛复盐酸舍曲林
【Key words】 electro-nape acupunctureDepressionSertraline HCL
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