【作者】 赵耀平；

【导师】 徐进康；

【作者基本信息】 南京中医药大学 ， 中医内科学， 2011， 硕士

【摘要】 目的：观察疏肝理气理气和胃法治疗慢性浅表性胃炎的临床疗效以及对患者生活质量、临床常见症状改善情况；探讨其作用机制。方法：采用随机对照研究,将符合研究标准的80例慢性浅表性胃炎患者随机分为治疗组和对照组。治疗组以疏肝理气和胃方治疗,辅以饮食调理、心理治疗。对照组以多潘立酮片和复方铝酸铋颗粒治疗；辅以饮食调理、心理治疗。两组均以4周为1个疗程,分别于治疗前、治疗后各观察一次,共观察1个疗程。主要观察两组疗效,治疗前后症状积分比较,胃镜检查改善情况,及生活质量改变以评定疏肝理气和胃法的临床疗效。采用SPSS16.0统计软件对相关数据进行处理,得出结论。结果：在改善各临床症状方面：两组各临床症状均能得到较大改善(P<0.05),在中医证侯疗效方面：两组中医证侯总积分均有明显改善(P<0.01),两组间比较治疗组的疗效优于对照组(P<0.05)；两组证候综合疗效比较,治疗组总有效率为91.5%,对照组总有效率为80.5%,两组比较有显著性差异(P<0.05)；在改善生活质量方面：两组多个维度的量表得分较治疗前有提高(P<0.05),而组间部分维度量表得分有明显差异(P<0.05).结论：两组均能显著地改善慢性浅表性胃炎患者各临床症状、中医证侯及生活质量；两组间比较,治疗组的治疗效果稍优于对照组,疏肝理气和胃法在治疗慢性浅表性胃炎患者方面具有良好的临床疗效,其突出疗效与其组方严谨、切中病机有关。提示中医药在本病的治疗上有一定的优势,有进一步研究和探讨的价值。更多还原

【Abstract】 Objective To observe the clinical curative effect of treating the type of Soothing of liver, adjusting qi and regulating stomach of chronic superficial gastritis, and the effect it caused to improve the quality of life and patient’s clinical symptoms, and explore the mechanism from clinical aspects.Methods 80 cases with CSG are divided into two groups at random. Soothing of liver, adjusting qi and regulating stomach Decoction was given to treatment group.The control group was given Much PanLi ketone and compound bismuth aluminate granules. two groups are supplemented by dietary conditioning and psychological treatment. Four weeks for a course of treatment, to observe the related symptoms symptoms gastroscopic effect and quality of life at respectively time when before treatment、after treatment, in order to assess the clinical curative effect of this method. SPSS16. statistical software will be used for processing data and drawing conclusions.Results In improving the clinical symptoms:two groups were greatly improved (P<0.05), In the syndromes of Chinese medicine efficacy:Clinical research showed that in the treatment group the total effective rate was91.5%, patho-effective rate was 80.5%; there has statistical significancet about total effective rate (p<0.05) and patho-effective rate in two groups. In improve the quality of life:more than two-dimensional degree of scale scores has been improved compared with before treatment, while the scores for each dimension between two groups was no significant.Conclusion Two groups are significantly improve patient’s clinical symptoms、syndromes in Chinese Medicine and the quality of life; compared the clinical curative effect, the treatment group is slightly better than the control group, This method have a good clinical efficacy, its outstanding efficacy is related to its rigorous structure and stringent hit the pathogenesis. Chinese medicine have certain advantages in treating this disease, and value to give further study and exploration value.更多还原