【作者】 赵微微；

【导师】 王伟明；

【作者基本信息】 山东中医药大学 ， 中医内科学， 2011， 硕士

【摘要】 目的:观察消溃愈疡方(灌肠)治疗湿热内蕴型溃疡性结肠炎(UC)的临床疗效,并初步探讨其作用机理。方法:临床选择符合纳入标准的湿热内蕴型溃疡性结肠炎患者60例,随机分为两组,试验组(30例)给予葛根芩连汤口服、消溃愈疡方灌肠,对照组(30例)给予葛根芩连汤口服、鸦胆子油灌肠,观察两组的临床疗效。结果:临床研究显示,试验组临床综合疗效、中医证候疗效、肠镜疗效及粘膜病理疗效均优于对照组(p<0.05或p<0.01)。试验组能明显改善脓血便、腹泻、腹痛、里急后重等症状,其疗效优于对照组(p<0.05或p<0.01)。两组临床治疗期间未发现明显不良反应。结论:消溃愈疡方(灌肠)是治疗湿热内蕴型UC的有效方剂,能够消除或改善临床症状,促进肠道黏膜溃疡面愈合,迅速缓解患者的痛苦。更多还原

【Abstract】 Objective: To observe the effect of Xiaokuiyuyangfang(XKYYF)(Enem.) on the Ulcerative colitis (UC) and explore the mechanism of it.Methods: 60 patients with UC were diveded into two groups at random :the treatment group and the control group. The treatment group was given XKYYF (Enem.) and GGQLT (p.o), the control group was given Brucea javanica oil emulsion injection (Enem.) and GGQLT (p.o). Symptoms and signs of each group were observed before and after the treatment, including enteroscopy and pathologic observing.Results:The treatment group’s synthesis effective of clinical the effective of syndrome of TCM、enteroscopy and pathologic observing are better than the control group’s (p<0.05 or p<0.01).XKYYF (Enem.) and GGQLT (p.o) canimprove more significantly the symptoms such as diarrhea、mucopurulent bloody stool and abdominal pain than Brucea javanica oil emulsion injection (Enem.) and GGQLT (p.o)(p<0.05 or p<0.01).更多还原