【作者】 周文静；

【导师】 张德宪；

【作者基本信息】 山东中医药大学 ， 中医内科学， 2011， 硕士

【摘要】 目的:研究青岛地区2型糖尿病的中医分型及特点,并阐述糖尿病各证型与各种客观指标的联系,从而为该病的中医规范化诊疗提供依据。方法:对青岛市海慈医疗集团2010年5月至2010年12月住院及门诊收治的613例T2DM患者进行临床分析。结果:1.筛选出五种中医证型:湿热困脾证14.5%、阴虚燥热证14.5%、气阴两虚证32.5%、气阴两虚兼血瘀27.4%、阴阳两虚证11.4%。发病特点:市区高于郊区,发病年龄集中于50-70岁。2.⑴从各组病程比较可以看出湿热困脾证<阴虚燥热证<气阴两虚证<阴阳两虚<气阴两虚兼血瘀。⑵各并发症例数按阴虚燥热组、气阴两虚证、气阴两虚兼血瘀证方向增多。糖尿病肾病、眼病等慢性并发症发生率随病程、年龄延长而增高。⑶T2DM中医各证型的BMI、HbAlc、血脂、与健康对照组比,均有统计学差异。湿热困脾的BMI、FPG、HbAlc、TC最高,其它三组之间的差别无统计学意义。结论:青岛地区最常见的2型糖尿病证型为5类:湿热困脾证、阴虚燥热证、气阴两虚证、气阴两虚兼血瘀、阴阳两虚证,以气阴两虚、气阴两虚兼血瘀最为多见。发病过程中易于夹瘀、夹痰湿、湿热,病位与肺脾肾联系密切。各T2DM中医证型与年龄、病程、慢性并发症等有统计学意义。更多还原

【Abstract】 Objective: To classify and analyze TCM syndrome types of type 2 diabetes mellitus in Qingdao, study the relations between each classification and the objective index,provide a basis and standard for judging the condition of patient. Method: There were 613 cases surveyed that came from the department of Endocrine ward and Clinic of Qingdao Haici Hospital. Results:1.There are 5 TCM syndrome types of T2DM selected: syndrome of Humid heat distressing spleen (14.5%), syndrome of pathogenic dryness-heat combined with deficiency of yin(14.5%), syndrome of deficiency on both qi and yin(32.5%),syndromes of deficiency on both qi and yin combined with blood stasis(27.4%),syndromes of deficiency on both yin and yang(11.4%) The incidence of T2DM in city is higher than outskirts and Village. The age range of onset for T2DM was between ages 50 and 70. 2.?⑴The comparison of course of disease in 5 TCM syndrome types: syndrome of Humid heat distressing spleen<syndrome of pathogenic dryness-heat combined with deficiency of yin<syndrome of deficiency on both qi and yin<syndromes of deficiency on both yin and yang<syndromes of deficiency on both qi and yin combined with blood stasis.⑵The incident of diabetic chronic complications was heightened by turns from syndrome of pathogenic dryness-heat combined with deficiency of yin, syndrome of deficiency on both qi and yin,syndromes of deficiency on both qi and yin combined with blood stasis.⑶To compare 5 TCM syndrome types of T2DM with healthy control group in the objective index including BMI,HbAlc,TC,TG, showed that there Was a statistical significance. And to compare syndrome of Humid heat distressing spleen with other five types showed that there was a statistical significance.?Conclusions: The most common types in Qingdao are syndrome of deficiency on both qi and yin and syndromes of deficiency on both qi and yin combined with blood stasis. During the course of illness It’s easy to turn to clip blood stasis and Humid heat. The location disease is closely linked to lungs, spleen and kidney. Each TCM syndrome types of T2Dm with TCM syndrome type age, duration, chronic complications have statistical significance.更多还原