当归拈痛丸配合水调散治疗急性期痛风性关节炎的疗效观察

【作者】 孙维晰；

【导师】 卫四来；

【作者基本信息】 辽宁中医药大学 ， 中医骨伤科学， 2011， 硕士

【摘要】 目的:观察当归拈痛丸配合水调散治疗急性期痛风性关节炎的临床疗效。材料与方法:将40例急性痛风性关节炎患者随机分为两组:观察组20例,用当归拈痛丸配合水调散治疗;对照组20例,用洛索洛芬钠片治疗。观察两组病例治疗前后临床症状、体征及血尿酸的变化情况,进行统计学处理而得出结果。结果:当归拈痛丸配合水调散对急性期痛风性关节炎具有良好治疗效果,在有效改善关节的红、肿、热、痛等临床症状及体征方面,与常规的西药治疗方案效果相似,两组间无显著性差异(P>0.05);在降低血尿酸方面,当归拈痛丸配合水调散要优于洛索洛芬钠片治疗;在安全性方面,观察组患者仅有2例出现轻微的腹泻、腹胀,未经处理症状自然消失,要优于对照组(12例出现不同程度恶心、呕吐等消化道反应)。结论:1、当归拈痛丸配合水调散治疗急性痛风性关节炎抗炎止痛作用与洛索洛芬钠片相似;2、当归拈痛丸配合水调散治疗急性痛风性关节炎能够有效降低血清中血尿酸水平,且优于洛索洛芬钠片无降尿酸作用;3、当归拈痛丸配合水调散治疗急性痛风性关节炎不良反应少,安全性高。更多还原

【Abstract】 Purpose:To observe the effect of Angelica pill for Relieving Pain associating with Shui Diaosan in treating the acute gout arthritisMaterial and method:40 patients were divided into two groups at random: the treatment group ( 20cases, treated with Angelica pill for Relieving Pain associating with Shui Diaosan ) and the control group (20 cases,treated with LoxoProfen Sodium Tablet ). Before and after treatment, the clinical symptoms,physical sign and the development of blood uric acid(BUA) were observed.Results: Angelica pill for Relieving Pain associating with Shui Diaosan can alleviate the reddness and swollen Pain of the acute gout arthritis,with the same function of LoxoProfen Sodium Tablet .After been examined by Ridit analysis(P>0.05),the difference has not statistical significant.In reducing serum uric acid, the Angelica pill for Relieving Pain associating with Shui Diaosan are better than loxoprofen sodium tablets;In security, the observation group were only 2 patients had mild diarrhea, abdominal distension, the symptoms disappear naturally without treatment, to be better than the control group (12 patients with varying degrees of nausea, vomiting and other gastrointestinal reactions.)Conclusion:1.Angelica pill for Relieving Pain associating with Shui Diaosan can alleviate the reddness and swollen Pain of the acute gout arthritis,with the same function of LoxoProfen Sodium Tablet .2.Angelica pill for Relieving Pain associating with Shui Diao san can reduce the blood uricaci .3.Angelica pill for Relieving Pain associating with Shui Diao san has little bad effect on the body.更多还原