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维、汉青少年暴力行为的事件相关电位对照研究

Study on Event-related Potential of Uygur and Han Violence Male Delinquents

【作者】 龙艳

【导师】 母代斌;

【作者基本信息】 新疆医科大学 , 精神病与精神卫生学, 2011, 硕士

【摘要】 目的:探讨男性青少年暴力行为的神经电生理基础。方法:以85例未成年管教所暴力型违法乱纪的青少年为研究组,40例正常普通中学生为对照组,进行脑诱发电位P300、N400测定。结果:(1)P300结果:与对照组比较,暴力组P2、P3潜伏期延长,靶P3、非靶P2波幅降低,差异均有统计学意义(P均<0.05)。维族暴力组较汉族暴力组靶N2潜伏期延长、P3波幅减低,差异均有统计学意义(P均<0.05)。(2)N400结果:与对照组比较,暴力组N400潜伏期延长,波幅降低,差异均有统计学意义(P均<0.05)。N400在Fz、Cz、Pz不同导联的潜伏期、波幅差异均无统计学意义(P>0.05)。结论:(1)有暴力攻击行为男性青少年对刺激的注意、定向和加工过程减弱,可能存在认知功能受损。维吾尔族暴力组认知功能受损可能较明显。(2)有暴力攻击行为男性青少年语言认知功能N400具有异常,可能存在语言认知功能受损。中央顶区(Fz、Cz、Pz) N400数据稳定性较好。

【Abstract】 Objective:To explore some neuroelectrophysiological bases underlying the aggression and violence in male delinquents.Methods:85 male delinquents with official records of violent violationand 40 normal controls were examined by resting brain evoked potentialsP300、N400. Results:(1) P300:compared with the normals, latency of the P2、P3 of the violence cases were prolonged, and amplitude of target P3 and non-target P2 were reduced significantly (P<0.05). Compared with the Han, latency of target N2 of the Uygurs were prolonged significantly and amplitude of target P3 were reduced significantly in violent crime group (P<0.05). (2) N400:Compared with the normals, latency of the N400 of the violence cases were prolonged, and amplitude of target N400 were reduced significantly (P<0.05), But mong Fz, Cz, Pz leads of latencies and amplitudes were not statistically different (P all> 0.05). Conclusion:(1)The male adolescents with acts of violence against have cognitive impairment, suggests that their attention, orientation and process to stimuli have weakened. Uighur violence group cognitive impairment may be lower. (2) The language of violence and aggressive behavior in male adolescents with abnormal cognitive function in N400, there may be language impaired cognition. Central parietal region (Fz, Cz, Pz) N400 data better stability.

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