【作者】 薛佳金；

【导师】 余国伟；

【作者基本信息】 浙江大学 ， 外科学， 2011， 硕士

【摘要】 目的：该项研究旨在观察、评估肺癌术后乳糜胸的发生规律和治疗效果。方法：通过对本科室自2010年1月起至2011年3月因肺部肿瘤行肺癌根治术的病例共607例行回顾性调查研究。统计术后乳糜胸发生率及治疗效果。比较开胸组与腔镜组术后乳糜胸的不同发生率。结果：肺癌根治术607例中8例发生术后乳糜胸,发生率1.32%。其中开胸组476例,乳糜胸4例,发生率0.84%。腔镜组131例,乳糜胸4例,发生率3.05%。胸腔镜手术并发乳糜胸可能性大于常规开胸手术(P<0.05)。两组病例在性别,年龄,病理类型方面比较无显著性差异(P>0.05)。8例乳糜胸患者中6例行保守治疗,1例行胸膜固定术,1例二次手术行胸导管结扎术。所有病例均成功治愈,无死亡病例。结论：本组肺癌根治术后乳糜胸发生率为1.32%。患者经过保守治疗可以治愈,预后良好。需要行二次手术的患者仅12.5%。更多还原

【Abstract】 Objective To investigate the morbidity of chylothorax after radical resection of pulmonary cancer and to evaluate its effectiveness of the treatments.Method This study was based on 607 patients with resection of lung cancer in our hospital from January,2010 to March,2011.8 patients had postoperative complication of chylothorax,for which retrospective study was performed.Results There are 8 chylothorax cases in 607 patients who underwent radical resection of lung cancer with the morbidity rate of 1.32%. Among them thoracotomy was used as the approach in 476 cases. The morbidity rate of the chylothorax was 0.84%(4/476). Thoracoscopy surgery was performed on 131 cases, the morbidity rate of the chylothorax is 3.05%(4/313). There is no significant difference in gender, age and the pathological aspect between two groups (P> 0.05). In these 8 patients of chylothorax,6 received conservative therapy,1 of them received pleurodesis,1 of them received ligation of thoracic duct in secondary operation. No postoperative mortality and morbidity were occurred for those patients. Conclusion In this retrospective study the morbidity of chylothorax is 1.32% in radical resection of lung cancer. Most of the patients were able to be cured by the conservative therapy with a satisfactory prognosis. Only 0.16 per cent patients need secondary surgical intervention.更多还原