【作者】 曾双林；

【导师】 谭利华；

【作者基本信息】 中南大学 ， 医学影像与核医学， 2011， 硕士

【摘要】 目的：应用MR相位对比法分析正常对照组(对照组)、梗阻性脑积水组(脑积水组)与慢性紧张型头痛组(头痛组)导水管平面脑脊液流量、流速及流动曲线。材料和方法：对照组26例,脑积水组10例,头痛组17例均应用3.0T磁共振扫描仪、CSF-QF CLEAR相位对比电影序列对导水管平面进行扫描,扫描数据输入电脑工作站应用脑脊液分析软件对脑脊液进行定性观察和定量测定。对比分析不同组别脑脊液流动曲线、流量、流速是否具有差别。结果：对照组导水管平面脑脊液呈与心脏博动相关的双向节律性流动。对照组脑脊液流动曲线呈平滑“U”型26例,波浪型1例。脑积水组呈平滑“U”型1例,波浪型9例。头痛组呈平滑“U”型11例,波浪型6例。对照组、脑积水组与头痛组导水管平面头侧脑脊液平均流量分别为0.235±0.157ml/s、0.068±0.099 ml/s、0.133±0.106 ml/s;足侧脑脊液平均流量分别为-0.358±0.201ml/s、-0.127±0.144 ml/s、-0.190±0.141ml/s;头侧脑脊液平均流速分别为6.023±2.654cm/s、1.590±1.652cm/s、3.479±2.364cm/s;足侧脑脊液平均流速分别为-8.263±3.020cm/s、-2.791±3.062cm/s-4.788±2.862cm/s;三组头侧与足侧脑脊液平均流量、流速两两比较均具有统计学义(P<0.05)结论：MR相位对比法能显示导水管平面脑脊液的流动节律,头侧、足侧方向的脑脊液流量与流速。对照组、脑积水组、头痛组导水管平面的脑脊液流动节律、头侧及足侧的脑脊液平均流量、流速均不同。更多还原

【Abstract】 Objective:To analyze the rate, velocity and curve of flow of cerebrospinal fluid (CSF) in the cerebral aqueduct of three groups of normal volunteers (control group), chronic tension headache patients (headache group) and obstructive hydrocephalus patients (hydrocephalus group) with cine phase contrast (cine-PC) magnetic resonance imaging.Materials and Methods:There were 26 of normal volunteers,17 of chronic tension headache and 10 of hydrocephalus who were scanned with CSF-QF CLEAR series of cine phase contrast on a Phillips Achieva 3.0T X-series MR unit. The data was transmitted to the computing workstation in order to analyze the rate, velocity and curve of flow of CSF in the cerebral aqueduct with software Extended MR Workspace R2.6.3. The groups were compared statistically.Results:The maps showed that the CSF in the cerebral aqueduct flowed bidirectionally in cardiac rhythm in control group. There were two types of the flow curves which like "U" or wave. The control group had 25 of U-curve and 1 of wave-curve, and the hydrocephalus group had 1 and 9, and the headache group had 11 and 6. In control, hydrocephalus and headache groups, the mean craniocaudal rate of flow of the CSF in the cerebral aqueduct was 0.235±0.157ml/s,0.068±0.099 ml/s and 0.133±0.106 ml/s respectively, and the mean caudocranial one was-0.358±0.201ml/s,-0.127±0.144ml/s and -0.190±0.141 ml/s respectively. The mean craniocaudal velocity of the CSF in the cerebral aqueduct was 6.023±2.654cm/s,1.590±1.652cm/s and 3.479±2.364cm/s respectively, and the caudocranial one was -8.263±3.020cm/s,-2.791±3.062cm/s and-4.788±2.862cm/s respectively. The difference of rate, velocity of flow of CSF in the cerebral aqueduct in three groups has statistical significance.Conclusion:Cine PC MRI is capable of demonstrating the rate, velocity and curve of flow of CSF in the cerebral aqueduct, which are different in control group, headache group and hydrocephalus group.更多还原