【作者】 周璟；

【导师】 刘小凡；

【作者基本信息】 成都中医药大学 ， 中医儿科学， 2011， 硕士

【摘要】 目的：本研究旨在通过观察服用膏方患儿哮喘缓解期前后症候自身对比,以及在常规治疗(参照本科哮喘治疗方法：服用中药,必要时坚持吸入用药)前提下,服用膏方和未服用膏方患儿的哮喘缓解期症候对比,客观评价膏方的临床疗效及安全性。方法：研究以60例符合小儿哮喘缓解期诊断,年龄在2岁以上患儿为对象,按1：1随机分为治疗组、对照组各30例,在常规用药情况下,系统观察并记录服用膏方患儿和未服用膏药患儿前后1年内哮喘发作次数、总天数及哮喘平时症候积分的变化并进行统计学分析。结果：1)治疗组显效率为93.3%,总有效率为100%；对照组显效率为40%,总有效率为93.3%,对照组与治疗组比较,显效率有显著差异(P<0.05),总有效率无显著差异(P>0.05)。2)两组在改善患儿平时症状及体征方面,均有显著性差异(P<0.05)。两组在喷嚏、流涕、动则气短、纳差或挑食、大便干或溏的改善上均有明显疗效,差异具有统计学意义(P<0.05),其中治疗组还对患儿四肢不温、自汗或盗汗、腰膝酸软、小便清长或遗尿、舌脉的改善有显著疗效(P<0.05),但对眼痒、鼻痒、睡眠欠佳、面色方面无显著性差异(P>0.05)。3)两组在改善患儿哮喘最严重一次发作主要症候程度均有显著差异(P<0.05),两组对比疗效无显著性差异(P>0.05)。但治疗组在减少哮喘发作次数、发作总天数均有显著差异(P<0.05)。对照组在治疗前后比较显示最严重一次哮喘发作程度有显著差异(P<0.05),哮喘发作次数、发作总天数无显著差异(P>0.05)。结论：冬令膏方应用于小儿哮喘缓解期,其显效率优于常规治疗组,总有效率与西药组相当,在缓解中医证侯方面和减少哮喘最严重一次发作程度,减少哮喘发作次数,天数方面疗效明显优于常规治疗组,且在治疗过程中均未出现不良反应,说明冬令膏方具有良好的安全性。同时冬令膏方在达到疗效的为患儿家属减轻了熬药的负担,表明冬令膏方具有良好的临床实用性,值得进-步推广。更多还原

【Abstract】 Objective: This study was designed to observe the self comparison Symptoms before and after taking the herbal paste, and under the premise of conventional treatment (Asthma treatment of our department:taking zhongyao, inhaled medication when necessary), taking the herbal paste group compare with not taking group in remission Stage of children asthma, objectively evaluate the clinical efficacy and safety of the herbal paste in the Sichuan region.Methods: Study found on 60 cases of children asthma remission, according to a 1:1 randomized into treatment group and control group 30 cases. They all Based on the conventional treatment, the treatment group was added with the winter herbal paste, and systematicly observed and recorded before and after treatment the most serious degree of asthma attacks, frequency and asthma remission symptom score and other changes were statistically analyzed.Results:1) the treatment Group with 93.3%.Excellence Rate and 100% total effective rate, the Control Group with 40% Excellence Rate and 96.6% total effective rate, there is obvious difference in Excellence Rate (P<0.05), but no obvious difference in total effective rate (P>0.05).2) The difference of Two groups of children in improving usually symptoms and signs were significant (P<0.05).The two groups in the improvement of sneezing, runny nose, shortness of breath after moving, poor appetite or Picky eating, dry stools or loose stools have significant effect, and the difference was statistically significant (P<0.05), Treatment group in the improvement of limbs coldness, spontaneous or night sweating, weak waist, urine long or enuresis, tongue and pulse have significant effects (P<0.05), but the improve of eye itching, nasal itching, poor sleep and complexion have no significant difference effect (P>0.05).3) The improving of the main symptom of the most serious asthma attack was significantly different degree in two group (P<0.05), there is not significantly different degree of effects in two group. Reduce the number of asthma attacks and total number of asthma attack days attack are significantly different degree in the treatment group (P<0.05). The improving of the main symptom of the most serious asthma attack was significantly different degree in conventional treatment group, but there is not significantly different degree of effects in reducing the number of asthma attacks and total number (P>0.05).Conclusions:Winter herbal paste applied to remission of asthma in children, its remarkable efficiency than conventional treatment group, The curative effects of reducing the most serious degree of asthma attacks, reducing the number and the number of days of asthma attacks Are better than conventional treatment group. In the course of treatment, there is no adverse reaction, demonstrate that party has a good security. At the same time reducing the children families of the burden of Aoyao.Demonstrate that Winter herbal paste has a good clinical utility, worthy of further promotion.更多还原