【作者】 刘宝；

【导师】 田理；

【作者基本信息】 成都中医药大学 ， 中医五官科学， 2011， 硕士

【摘要】 目的：系统观察苓桂术甘汤加味治疗常年性变应性鼻炎发作期痰饮上犯证的临床疗效。方法：将符合诊断标准的105例常年性变应性鼻炎发作期痰饮上犯证患者随机分为治疗组(52例)和对照组(53例),治疗组予苓桂术甘汤加味口服,对照组予氯雷他定片口服,疗程为14天。定期复诊,观察并记录治疗过程中两组患者临床症状、体征的变化及不良反应。疗程结束后对积分进行统计学分析,判定疗效。结果：在试验组52例与对照组53例中,两组患者治疗前后症状比较,治疗组与对照组相比有统计学意义(P<0.05),提示治疗组治疗PAR临床症状积分与对照组比较有差异。治疗组显效率为46.15%,总有效率为76.92%；对照组显效率为24.53%,总有效率为58.49%。两组疗效经非参数秩和检验,统计量Z等于-2.489,P<0.05,差异具有统计学意义,说明治疗组疗效优于对照组14.43%。结论：对于常年性变应性鼻炎发作期痰饮上犯证,使用苓桂术甘汤加味治疗,以人体的阴阳转化为特征,益气健脾,温阳化饮为其治疗大法,谨守病机,谨察阴阳所在而调之,以平为期,疗效好,不良反应少,具有临床推广价值。更多还原

【Abstract】 Objective:Observe the therapeutic effect of the treatment to PAR with Decoction Linguizhugantang.Methods:Divide 105 patients with PAR of adverse phlegm pattern randomly into trial group and control group,52 cases in trial group, and 53 cases in control group. Treat the trial group with oral decoction Linguizhugantang modified, while control group with oral Lomtadine, both for 14 days. The patients should accept further consultations regularly, during which the processing of symptoms, physical signs, and untoward effects of both groups should be observed. Analyze the integral by statistics and the end of treatment period, and judge the therapeutic effects.Results:Between the trial group and the control group, there’re significant differences on anterior and posterior symptoms (P＜0.05), which refers to that the symptom integral of trial group is superior to the control group. The excellence of trial group is 46.15%, and the total cure rate of which is 76.92%. The excellence of control group is 24.53%, and the total cure rate of which is 58.49%. Via the Kruskal-Wallis Test, the statistics Z equals to -2.489, P＜0.05, there’s statistical difference.Conclusion:To cure the PAR of adverse phlegm pattern differentiation, the applications of Linguizhugantang modified has a fine therapeutic effect with few untoward effects, taking the converting of Yin and Yang in human body as its character, and tonifying spleen-qi to expel the phlegm, which is worth of popularization.更多还原