【作者】 刘鸿；

【导师】 谢建兴；

【作者基本信息】 广州中医药大学 ， 中医学， 2011， 硕士

【摘要】 背景前列腺炎(prostatitis)是由于前列腺受到微生物等病原体感染或某些非感染因素刺激而发生的炎症反应,及由此造成的患者前列腺区域不适或疼痛、排尿异常、尿道异常分泌物等临床表现,是一种男性患者中较为常见的且让人十分困扰的疾病。但运用中西医结合治疗可有效地缓解其导致的具有各种独特形式的综合征(前列腺炎综合征)。在出现前列腺炎综合征的患者当中,约有90~95%被诊断为Ⅲ型前列腺炎。其病因中心可能是感染、炎症和异常的盆底神经肌肉活动的共同作用。症状除表现有排尿异常,疼痛不适及性功能异常之外,更有对患者造成精神上的压力,而精神紧张亦加重各种不适的症状。本病治疗上可予中西医结合法,能有效缩短疾病病程,缓解酶床症状。目的评价清热利湿中药坐浴方配合中成药治疗慢性前列腺炎证属湿热蕴结证患者的临床疗效。方法把符合诊断标准的60例慢性前列腺炎患者,随机按1：1：1分为中药坐浴+前列舒通胶囊治疗组、热水坐浴+前列舒通胶囊治疗组、前列舒通胶囊治疗组。中药坐浴+前列舒通胶囊组：中医辨证为湿热蕴结证,以清热化湿坐浴方配合口服前列舒通胶囊：每日中药坐浴1次,并按说明口服前列舒通胶囊,治疗疗程为1月。热水坐浴+前列舒通胶囊组：每日温水坐浴1次,并口服前列舒通胶囊,治疗疗程1月。前列舒通胶囊组：单单口服前列舒通胶囊,治疗疗程是1月。所有患者均于治疗前和治疗后1个月进行NIH-CPSI症状积分。疗程结束后观察两组在治疗前后NIH-CPSI积分的变化,通过SPSS18.0对数据进行统计分析,以综合评价中药坐浴对慢性前列腺炎患者症状缓解的效果。结果各组治疗后组间对照比较,差异具有统计学意义(P<0.05)。三组治疗各自前后对照比较,差异均有统计学意义(P<0.05)。结论1.前列舒通胶囊治疗湿热蕴结型慢性前列腺炎有一定的疗效。2.中药坐浴、热水坐浴联合前列舒通胶囊治疗湿热蕴结型慢性前列腺炎的疗效优于单用前列舒通胶囊组的疗效,并对疼痛症状有较好的缓解作用,尤其以中药坐浴为优,具有良好的研究及临床应用前景,是安全的,可行的方法之一。更多还原

【Abstract】 Background:Prostatitis occurred due to infection of microbial pathogens or un-infected inflammation in prostate gland. Sufferer will feel discomfort or pain in the prostate gland, abnormal micturition, and abnormal substance in urethra in clinical manifestation. This is a common but very trouble illness. When combine western and eastern medication can effectively relief prostatitis. 90% to 95% of sufferers of prostatitis are typeⅢprostatitis. The origin of the illness can be infection, inflammation, or abnormal active of Pelvic floor neuromuscular. Symptoms include abnormal micturition, discomfort, pain, and abnormal sexual function. It also put sufferer under great stress, intense pressure also worsen the illness.Objectives:Evaluate the effect of sit bath of qing re li shi herbs with Chinese medicine to heal chronicprostatitis of shi re yun jieMethods:Separate 60 patients who qualify as the sufferer of standard prostatitis into three different treatment groups:By 1:1:1 into the forefront of sit bath of Qingrelishi herbs+Qianlieshu Capsule treatment Group, warm water shit bath+Qianlieshu capsule treatment group, Qianlieshu capsule treatment group. sit bath of Qingrelishi herbs+Qianlieshu Capsule Group: TCM as Shireyunjie Accumulation card in order to side with sit bath of Qingrelishi herbs ltime each day for a month, and also with Qianlieshu capsule. Hot Water Bath+Qianlieshu capsule group:warm water sit bath ltime each day, and have Qianlieshu capsule for a month. Qianlieshu Capsule Group: Just have to have Qianlieshu capsule only.All patients before treatment and a month after treatment have to check NIH-CPSI symptom scores. After the treatment, before and after treatment were observed in the NIH-CPSI score by SPSS18.0 statistical analysis of the data, an integrated the evaluation of sit bath to the chronic prostatitis. After the treatment ended, we will compare the NIH-CPSI points and Chinese medicine evaluation, analyst SPSS18.0 data for statistical analysis, then cross reference the effect of various results of the treatment.Result:Compare the results of each treatment group, the differences are statistical significant(P<0.05). Compare the results of prior and post treatments of each treatment group, the differences are statistical significant(P<0.05).Conclusion:1. Treatment with Qianlieshutong capsule of chronic prostatitis have a certain effect.2. Chinese sit bath, hot water bath treatment with Qianlieshutong capsule are better than single capsule group Qianlieshutong capsule, and better pain relief, particularly in traditional Chinese medicine to sit Bath is excellent. And it has favourable research Perspective.It’s also safe and feasible.更多还原