【作者】 曹云松；

【导师】 任可；

【作者基本信息】 北京中医药大学 ， 中医内科学， 2011， 硕士

【摘要】 高血压肾损害指高血压病导致肾脏功能和结构的改变。美国肾脏数据系统(USRDS)的资料表明,高血压病一直是导致ESRD的第二位原因；多危险因素干预研究(MRFIT)资料显示,大约49%的ESRD是由高血压引起；截止到2002年,我国大约有高血压患者1.6亿人,高血压患病率为18.8%；我国全部透析患者中,约9.6%是由于高血压肾动脉硬化症引起。中医文献中,并无确切的病名与高血压肾损害相对应。目前中医对高血压肾损害的认识还存在着局限性、辨证不统一等问题。高血压肾损害患者的中医体质分型呈现何种分布规律,至今没有此方面的调查研究。目的：本课题通过对33例早中期高血压肾损害患者的中医体质分布进行观察统计,旨在发现早中期高血压肾损害的中医体质学特点及内在规律,为探讨该病提供另一种途径,从而更好的完善中医药预防治疗高血压肾损害的理论,对临床也具有一定的指导意义。方法：本课题采用北京中医药大学王琦教授设计的9种体质类型分类方法,对每个入选病例的进行现场填写调查问卷；以搜集到北京中医药大学东方医院33例早中期高血压肾损害患者的临床资料为依据,运用数据描述方法,对早中期高血压肾损害患者的中医体质特点及内在规律进行初步探讨。结果：1、调查后按体质转化分小于主要体质分值,但转化分大于40分者,认为存在兼夹体质情况,所调查人群中基本存在一种或多种兼夹,其中有重复情况存在。2、初步判定,早中期高血压肾损害患者性别上与中医体质分布无相关性。结论：1、9种中医体质分型中,早中期高血压肾损害最主要的体质类型为阴虚质,易感性较其它体质者均高；2、在兼夹体质和倾向体质中,气虚质在早中期高血压肾损害中出现率均为最高；其它体质均参与了该病发生发展；3、早中期高血压肾损害的发生发展,是以一种或几种体质为主,多种体质因素共同参与的结果。更多还原

【Abstract】 Study on the traditional Chinese medical Constitution of hypertension nephrosclerosis (HN)Hypertension nephrosclerosis (HN) refers to the change of kidney structu re and function caused by hypertension in clinical. The United States Renal Data System (USRDS) data show that,Hypertension has been the second reason lead the ESRD in United States. Research of Multiple risk factor interventio n (MRFIT)found that about 49% of ESRD caused by hypertension. Statistics of 2 002 show that,Adult prevalence of hypertension was 18.8% in china,and about 160 million people with hypertension patients in china.According to 1999 s tatistics,all Hemodialysis patients in China,9.6% of benign arteriolar neph rosclerosis Hypertension, there are no precise Name Correspondingly in the t raditional Chinese medicine,Traditional Chinese Medicine understanding of H ypertension nephrosclerosis,there are still limits, differentiation is not u niform and so on. Whether patients with Hypertension nephrosclerosis in whic h the human constitution and more.What distribution of traditional Chinese medical Constitution type,There has been no research in this area.Objective:In this research, according to observe and statistic the TCM constitution about 33 cases of early and medial stages hypertension nephros clerosis, we try to found the characteristic and distributed rule of the TCM constitution of early and medial stages HN,To better perfect the theory of TCM prevention and treatment about HN, Also has provide some clinical Guide significance.Method:The subject with Beijing University of Chinese Medicine Qi Wang Professors’9 constitution classification, and each of the selected cases we re filled out the questionnaire; In accordance with 33 early and medial stag es hypertension nephrosclerosis patients’clinic data provided by Dongfang h ospitals in Beijing and using the data description method, this study Discus sed the TCM constitution Features and distributed rule of early and medial stages hypertension nephrosclerosis.Results:1. In accordance with the transformed scores is less than the main constitution scores,but the transformed scores is more than 40 points, that determine there are have and complex by constitution. In study populati on have existence one kind or several complex by constitution, and there hav e repeat existence; 2. Preliminary determination,There is no correlation in s ex and distributed rule of the TCM constitution. Conclusions:1. In 9 kinds of TCM constitution, Qi stagnation constitutio n was the primary of early and medial stages hypertension nephrosclerosis, and susceptibility were higher than other constitutions; 2. Both in complex by constitution and prone to constitution,Qi deficiency is the highest occu rrence rate of early and medial stages hypertension nephrosclerosis, other c onstitution were participate occurrence and development of this disease;3. In the occurrence and development of early and medial stages HN, was the dev elopment of one or several constitution primarily, and various constitutio n factors common participation of results.更多还原