【作者】 张彦；

【导师】 汪冰；

【作者基本信息】 山东中医药大学 ， 中医五官科学， 2008， 硕士

【摘要】 慢性咽炎是临床常见症、多发病,其临床表现为以咽喉干燥,痒痛不适,咽内异物感或灼热感、干咳少痰等为主要特征。中医药治疗该病有独特的优势。本课题应用中医理论及现代技术,从临床与实验两方面观察了导师汪冰教授用于临床多年的经验方养阴利咽汤治疗慢性咽炎的疗效。临床观察中,口服养阴利咽汤治疗慢性咽炎70例,治愈率38.85%,总有效率94.29%,明显优于西药对照组(P<0.01)。实验研究采用药理学、组织学以及生物化学方法,制造家兔、小鼠和大鼠的不同病理模型,结果表明养阴利咽汤具有良好的抗炎、抑菌、化痰、止咳、改善微循环等作用,从而达到治疗慢性咽炎的目的。更多还原

【Abstract】 Chronic pharyngitis(CP) have an higher attack of rate and the most obvious syndromes are that pharyngalgia,dry throat,tussiculation,dry cough,pharyngeal hot feeling,foreign body sensation of pharynx etc.The Traditional Chinese Medicine has special advantage in the aspects of curing CP. This project was selected to seek an effective recipe in treating CP and to study the treating mechanism of it. In the guidance of the theory of traditional Chinese medicine and clinical practice, the cause and pathogenesis on is reviewed in the article. And curative effect and mechanism of Yangyinliyantang(YYLYT) treating CP is researched systematically. In clinical study,70 cases of CP were treated with YYLYT, the clinical cure rate is 38.85%, the total effective rate is 94.29%. The curative effect is better than that of the control group(P<0.01). Pharmacological procedures were utilized to investigate these effects of YYLYT as anti-inflammation, Qi-regulating and phlegm-transformation, and preventive treatment on various kinds of animal model induced among mice, rats or rabbits respectively, supplemented by histopathological and biochemical procedure.Experimental research indicates:preventive and therapeutic effects of YYLYT on CP should be associated with its inhibitng effect on inflammatory changes and to the improving effect blood rheoolgy in pharyngeal mucosa.更多还原