节点文献
多足配体钙镁金属配合物的合成、结构表征及其抑菌活性研究
Sythesis, Structural Characterization and Antibacterial Activity of Magnesium and Calcium Complexes with Podand Ligands
【作者】 赵增兵；
【作者基本信息】 青海师范大学 ， 无机化学， 2010， 硕士
【摘要】 水合肼双缩邻甲酰基苯磺酸钙配合物属单斜晶系,空间群为P2(1)/c,晶胞参数：a=10.4202(12)(?),b=6.5879(10)(?),c=17.659(2)(?),β=95.625(2)°,Dc=1.516g/cm3, V=1206.4(3)(?)3,Z=2,μ=0.502mm-1,F(000)=576,结构偏差因子R1=0.0299,wR2=0.0765。该配合物无抑菌活性。二乙烯三胺双缩邻甲酰基苯甲酸钙钠双核配合物属三角晶系,空间群为P-31c,晶胞参数为：a=16.8639(18)(?),b=16.8639(18)(?),c=15.4992(14)(?),α=90.00°,β=90.00°,γ=120.00°,Dc=1.211g/cm3,V=3817.3(7)(?)3,Z=1,μ=0.164mm-1,F(000)=1475,结构偏差因子R1=0.0871,wR2=0.2480。该配合物具有抑菌活性。2-甲基-5-吡嗪羧酸钙配合物属三斜晶系,空间群为P-1,晶胞参数为：a=7.8613(11)(?),b=8.8903(13)(?), c=12.2678(15)(?),α=83.348(2)°,β=77.9320(10)°,γ=70.1330(10)°,Dc=1.477g/cm3, V=787.60(19)(?)3,Z=2,μ=0.434mm-1,F(000)=364,结构偏差因子R1=0.0566,wR2=0.1342。该配合物无抑菌活性,而配体有抑菌活性。4-氨基-3-甲基苯甲酸邻菲啰啉钙配合物属三斜晶系,空间群为P-1,晶胞参数为：a=13.2651(15)(?),b=7.0020(10)(?),c=23.862(2)(?),β=113.690(2)°,Dc=1.353g/cm3,V=2029.6(4)(?)3,Z=2,μ=0.222mm-1,F(000)=872,结构偏差因子R1=0.0353,wR2=0.0833。该配合物具有抑菌活性。N-对甲基苯磺酰-α-苯丙氨酸镁配合物属单斜晶系,空间群为P2(1),晶胞参数为：a=9.5290(10)(?),b=45.040(4)(?),c=9.5662(11)(?),β=102.770(2)°,Dc=1.313g/cm3,V= 4004.1(7)(?)3,Z=1,μ=0.216mm-1,F(000)=1674,结构偏差因子R1=0.0816,wR2=0.2088。该配合物和其配体均无抑菌活性。N-苯磺酰-α-苯丙氨酸邻菲啰啉镁配合物属三斜晶系,空间群为P-1,晶胞参数为：a=7.0870(10)(?),b=13.2480(15)(?),c=16.218(2)(?),α=111.854(2)°,β=101.3000(10)°,γ=95.6450(10)°,Dc=1.300g/cm3,V=1361.1(3)(?)3,Z=1,μ=0.176mm-1,F(000)=558,结构偏差因子R1=0.0683,wR2=0.1596。该配合物具有抑菌活性,而配体无抑菌活性。3-乙氧基水杨醛缩4-氨基-3-甲基苯磺酸镁配合物属单斜晶系,空间群为C2/c,晶胞参数为：a=38.710(11)(?),b=7.531(2)(?),c=13.087(3)(?),β= 104.986(4)°,Dc=1.444g/cm3,V=3685.6(17)(?)3,Z=4,μ=0.237mm-1,F(000)=1688,结构偏差因子R1=0.0318,wR2=0.0847。邻甲酰基苯甲酸缩氨基硫脲镁配合物属单斜晶系,空间群为P2(1)/c,晶胞参数为：a=12.952(2)(?),b=8.9082(13)(?),c=11.5365(17)(?),β=95.160(2)°,Dc=1.445g/cm3,V=1325.7(3)(?)3,Z=2,μ=0.286mm-1,F(000)=604,结构偏差因子R1=0.0514,wR2=0.1280。邻甲酰基苯磺酸缩氨基硫脲锰配合物属三斜晶系,空间群为P-1,晶胞参数为：a=6.8096(6)(?),b=9.5498(8)(?),c=10.7898(9)(?),α=64.3860(10)°,β=88.4950(10)°,γ=83.7910(10)°, Dc=1.700g/cm3,V=628.83(9)(?)3,Z=1,μ=0.921 mm-1, F(000)=331,结构偏差因子R1=0.0282,wR2=0.0745。邻甲酰基苯磺酸钠缩氨基硫脲钠配合物属单斜晶系,空间群为P2(1)/c,晶胞参数为：a=7.4065(5)(?),b=8.7359(6)(?), c=25.2100(18)(?),β=98.2920(10)°, Dc=1.600g/cm3,V=1614.10(19)(?)3, Z=4,μ=0.557mm-1, F(000)=804,结构偏差因子R1=0.0545,wR2=0.1588。化合物4-二乙氨基水杨醛缩4-氨基-3-甲基苯磺酸属单斜晶系,空间群为P2(1)/n,晶胞参数为：a=8.230(9)(?),b=12.143(14)(?),c= 18.96(2)(?),β=96.848(19)°, Dc=1.279g/cm3, V=1882(4)(?)3, Z=4,μ=0.196mm-1, F(000)=768,结构偏差因子R1=0.0459,wR2=0.1266。
【Abstract】 The compound [Ca(2-formyl-benzenesulfonate-hydrazine)(H2O)4]·4H2O belongs t o monoclinic, space group P2(1)/c with a=10.4202(12)(?),b=6.5879(10)(?), c=17.659(2) (?),β=95.625(2)°,Dc=1.516g/cm3, V=1206.4(3)(?)3, Z=2,μ=0.502mm-1, F(000)=576, R1 =0.0299, wR2=0.0765. The complexes not show antibacterial activity. The compound [Na(H2O)6][Ca(2-carboxybenzaldehyde-diethylenetriamine)3]·3H2O belongs to trigonal, space group P-31c with a=16.8639(18)(?),b=16.8639(18)(?), c=15.4992(14)(?),α=90.00°,β=90.00°,γ=120.00°, Dc=1.211g/cm3, V=3817.3(7)(?)3, Z=1,μ=0.164mm-1,F(000)=14 75,R1=0.0871, wR2=0.2480. The complexes show antibacterial activity. The compoun d [Ca(C6H5O2N2)2]·2H2O belongs to triclinic, space groupP-1 with a=1.8613(11)(?), b =8.8903(13)(?), c=12.2678(15)(?),α=83.348(2)°,β=77.9320(10)°,γ=70.1330(10)°, Dc=1. 477g/cm3, V=787.60(19)(?)3, Z=2,μ=0.434mm-1, F(000)=364, R1=0.0566, wR2=0.1342. The complexes do not show antibacterial activity, and the ligand do. The compoun d [Ca(phen)5H2O](phen)(4-amino-3-methylbenzoic acid)2·2H2O belongs to triclinic, sp ace group P-1 with a=13.2651(15)(?),b=7.0020(10)(?), c=23.862(2)(?),β=113.690(2)°, V =2029.6(4)(?)3, Z=2,Dc=1.353g/cm3, F(000)=872,μ=0.222mm-1,R1=0.0353, wR2=0.083 3. The complexes show antibacterial activity.The compound [Mg(N-4-methylbenzenesulphony-L-phenylalanine)2(H2O)4]2[Mg(N-4-methylbenzenesulphony-L-phenylalanine)(H2O)5]2(N-4-methylbenzenesulphony-L-phenylala nine)2·11H2O belongs to monoclinic, space group P2(1) with a=9.5290(10)(?),b=45.040 (4)(?), c=9.5662(11)(?),β=102.770(2)°, Dc=1.313g/cm3, V=4004.1(7)(?)3, Z=1,μ=0.216 m m-1, F(000)=1674, R1=0.0816, wR2=0.2088. The complexes and the ligands do not sho w antibacterial activity. The compound [Mg(N-benzenesulphony-L-phenylalanine)2(phen) (H2O)2](phen)·2H2O belongs to triclinic, space group P-1 with a=1.0870(10)(?), b=13. 2480(15)(?), c=16.218(2)(?),α=111.854(2)°,β=101.3000(10)°,γ=95.6450(10)°, V=1361.1 (3)(?)3, Z=1,Dc=1.300g/cm3,F(000)=558,μ=0.176cm-1, R1=0.0683, wR2=0.1596. The co mplex show antibacterial activity, and the ligand do not. The compound [Mg(H2O)6] (3-ethoxysalicyladehyde-4-amino-3-methyl benzenesulfonate)2 belongs to monoclinic, spa ce group C2/c with a=38.710(11)(?),b=7.531(2)(?), c=13.087(3)(?),β=104.986(4)°,Dc=1. 444g/cm3, V=3685.6(17)(?)3, Z=4,μ=0.237mm-1, F(000)=1688,R1,=0.0318,wR2=0.0847. The compound [Mg(H2O)6](2-carboxybenzaldehyde-thiosemicarbazide) belongs to mono clinic, space group P2(1)/c with a=12.952(2)(?),b=8.9082(13)(?),c=11.5365(17)(?),β=95. 160(2)°,Dc=1.445g/cm3,V=1325.7(3)(?)3,Z=2,μ=0.286mm-1,F(000)=604, R1=0.0514,w R2=0.1280.The compound Mn(2-formyl-benzenesulfonate-thiosemicarbazide)2(H2O)4 belongs t o triclinic, space group P-1 with a=6.8096(6)(?),b=9.5498(8)(?), c=10.7898(9)(?),α=64.3 860(10)°,β=88.4950(10)°,γ=83.7910(10)°,Dc=1.700g/cm3,V=628.83(9)(?)3,Z=1,μ=0.9 21mm-1, F(000)=331,R1=0.0282,wR2=0.0745. The compound [Na(2-formyl-benzenesu lfonate-thiosemicarbazide)Cl]·4H2O belongs to monoclinic, space group P2(1)/c with a =7.4065(5)(?),b=8.7359(6)(?), c=25.2100(18)(?),β=98.2920(10)°,Dc=1.600g/cm3, V=1614. 10(19)(?)3, Z=4,μ=0.557mm-1,F(000)=804,R1=0.0545,wR2=0.1588. The compound 4-Diethylaminosalicylaldehyde-4-amino-3-methyl benzenesulfonate belongs to monoclinics pace group P2(1)/n with a=8.230(9)(?),b=12.143(14)(?),c=18.96(2)(?),β=96.848(19)°,D c=1.279g/cm3,V=1882(4)(?)3, Z=4,μ=0.196mm-1, F(000)=768,R1=0.0459,wR2=0.1266. Key Words:calcium, magnesium, synthesis, crystal structure, antibacterial activity
【Key words】 calcium； magnesium； synthesis； crystal structure； antibacterial activity；