【作者】 周思薇；

【导师】 陈孟溪； 张红；

【作者基本信息】 湖南中医药大学 ， 中西医结合临床， 2010， 硕士

【摘要】 目的：观察导师清热散瘀解毒方治疗癌性发热的临床疗效。方法：研究采用随机对照试验的方法,将符合诊断、纳入标准的受试对象按进入观察时的先后顺序按随机数字表法随机分为治疗组和对照组。两组都给予相同的基础治疗。针对癌性发热,治疗组用导师自拟清热散瘀解毒方口服治疗。对照组用吲哚美辛栓塞肛治疗,7天为一疗程。对两种治疗方法在退热疗效、卡氏评分、退热幅度等方面进行比较。分析清热散瘀解毒法治疗癌性发热的疗效。结果：(1)清热散瘀解毒方对癌性发热退热疗效的影响：治疗组总有效率80%,对照组总有效率53.33%,p<0.05,具有统计学差异。(2)清热散瘀解毒方对癌性发热病人退热幅度的影响：经t检验对比治疗组与对照组,统计学有显著差异(p<0.01)。(3)清热散瘀解毒方对癌性发热患者白细胞计数的影响经与对照组对比不具有统计学差异(p>0.05)。(4)清热散瘀解毒方对癌性发热病人卡氏评分的影响：治疗前后治疗组增加稳定率为90%,对照组增加稳定率为83.33%。对比具有统计学差异。结论：(1)清热散瘀解毒方能够明显改善患者的临床症状、提高生活质量。(2)清热散瘀解毒方能够明显提高退热幅度。(3)清热散瘀解毒方对白细胞计数的影响不大。更多还原

【Abstract】 Objective:Observation by the clinical efficacy of the method of Qingre Sanyu Jiedu Therapy in the treatment of tumor-induced fever.Methods:Explore the method of randomized controlled trials, randomly divided the experimental objects who in line with diagnosis into treatment group and control group. The two groups were given the same basic treatment. For tumor-induced fever, the treatment were treated by take Qingre Sanyu Jiedu Therapy which created by teacher, Control group were treated by indomethacin suppository cork the anus, a treatment for seven days. Compare the Two kinds of treatment methods in the Composite efficacy, Karnofsky score, fever range, etc. for comparison. Compare the results, analysis of the efficacy of the method of benefiting vital energy,so as to analysis the treatment of tumor-induced fever by Qingre Sanyu Jiedu Therapy. Results:(1) Compare the effect of Qingre Sanyu Jiedu Therapy with comprehensive treatment:the treatment group, the total efficiency is 80%,the control group, the total efficiency is 53.33%, the treatment group than the control group. p<0.05, It has statistically significant.(2) Compare the effect of Qingre Sanyu Jiedu Therapy with fever of the magnitude of impact:by the T test comparing the treatment group compared with the control group were significantly different (p<0.01).(3) Compare the effect of Qingre Sanyu Jiedu Therapy with cancer of white blood cell count,p>0.05, that its meaningless.(4) Compare the effect of Qingre Sanyu Jiedu Therapy with fever Karnofsky score impact:the treatment group before and after treatment Karnofsky score increase the stability rate of 90%.In the control group Karnofsky score increase stability rate of 83.33%. p<0.05, It has statistically significant.Conclusion:The results of this study shows that in the treatment tumor-induced fever, the effete of Qingre Sanyu Jiedu therapy can effectively improve the patients’living quality、cooling rate and the clinical symptoms exactly. But its meaningless to the white blood cell count.更多还原