【摘要】 目的基于芦山地震伤病员疾病谱的实际药品使用情况,分析四川大学华西医院芦山地震应急药品使用的合理性。方法以用药频度(DDDs),药物利用指数(DUI)为评价指标,采用Excel软件进行数据录入,统计分析芦山地震后1月内四川大学华西医院收治伤病员应急救治药品的使用情况是否为其伤情/病情所需及其合理性。结果震后1周,地震伤员以外伤和伤口感染类为主,主要选用抗菌药物。震后4周,地震病员以非外伤性疾病和内科疾病为主,主要选用呼吸系统、消化系统用药。在可计算DUI值的49种药物中,注射给药多于非注射给药(59.18%vs.40.82%)。DUI值=1者仅12.24%。DUI值<1者(均值:0.65)占38.78%,提示用药量不足。DUI值>1者(均值:1.77)占46.94%,提示用药可能过度。结论震后1月内四川大学华西医院各系统疾病用药基本为对症对因用药,且用药及时。采用常态下DUI=1判断应急药品使用合理性尚需进一步证实。更多还原

【Abstract】 Objective To analyze the rationality of emergency medication in the West China Hospital ater Lushan earthquake based on the actual drug use of earthquake victims.Methods We applied DDDs and DUI as evaluation index,input data using Excel sotware,and analyzed if the emergency medication was required for the injury/illness and the rationality of emergency medication.Results Earthquake victims mainly had trauma and wound infection and they were given antibiotics as main treatment one week ater the earthquake.Drugs for the respiratory system and digestive system were mainly used in patients who mainly manifested as non-traumatic diseases and internal diseases four weeks ater the earthquake.Among 49 kinds of drugs which could be calculated for the value of DUI,injection accounted for a larger proportion than non-injection(59.18% vs.40.82%).he results showed that,the medication(DUI=1) only accounted for 12.24%;the medication(DUI<1,Mean=0.65) accounted for 38.78%,which implied insuicient drug use;the medication(DUI>1,Mean=1.77) accounted for 46.94%,which implied drug overuse.Conclusion Medication for every system is basically timely and rational when treating symptoms and causes in the West China Hospital within one month ater Lushan earthquake.However,the rationality of emergency medications using DUI=1 under normal conditions still needs to be further veriied.更多还原