【摘要】 目的研究复方丁香挥发油的提取和包合工艺。方法以提取的挥发油体积为评价指标,采用正交设计优选水蒸气蒸馏法提取丁香、砂仁和胡椒三味中药中的挥发油的最优条件;以包合率为评价指标,采用单因素实验和正交实验,优选最佳的包合工艺条件。结果复方丁香挥发油的最佳提取工艺条件为:药材加8倍水量,浸泡2.5h,加热蒸馏提取6h,挥发油平均含量为4.74%;复方丁香挥发油包合物的最佳条件为:挥发油与β-CD比例为1∶8,包合温度为40℃,包合时间为4h,洗涤溶剂为石油醚,干燥温度为40℃,挥发油平均包合率为81.5%。结论优选的提取工艺和包合工艺条件科学、合理、可行。更多还原

【Abstract】 Objective To study the extraction and inclusion of volatile oil from compound clove. Methods Using the extracted volatile oil volume as the evaluation index,the optimum conditions for extraction of volatile oil from traditional Chinese medicine of clove,parsley and pepper were optimized by orthogonal design. Taking the inclusion ratio as the evaluation index,a single factor experiment and orthogonal experiment were carried out to optimize the optimal conditions of the inclusion process. Results The optimum conditions for extraction of compound clove volatile oil were as follows :8 times water was added to medicinal materials,the soaking time was 2.5 hours,the heating distillation extraction time was 6 hours,and the average volatile oil content was 4.74 %. The optimum conditions for compound clove volatile oil inclusions were as follows :The ratio of volatile oil to β-CD was 1 ∶ 8,the inclusion temperature was 40℃,the inclusion time was 4 hours,the washing solvent was petroleum ether,the drying temperature was 40℃,and the average inclusion rate of volatile oil was 81.5 %. Conclusion Optimized extraction process and Inclusion process were scientific,reasonable and feasible.更多还原