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《中国药典》收载的钩藤基原植物吲哚生物碱研究进展
Advances in indole alkaloids from traditional Chinese medicine of Uncariae Ramulus Cum Uncis documented in Chinese Pharmacopoeia
【摘要】 茜草科Rubiaceae钩藤属Uncaria植物全世界有34种,我国11种、1变型,《中国药典》收载钩藤U. rhynchophylla、大叶钩藤U. macrophylla、毛钩藤U. hirsuta、华钩藤U. sinensis和无柄果钩藤U. sessilifructus作为中药钩藤的基原植物。钩藤属植物特征性成分为吲哚生物碱,此外还含有三萜、木脂素、黄酮等。为了进一步明确中药钩藤的活性物质基础以及不同部位化学成分差异,该文对以上5种钩藤基原植物中的吲哚生物碱研究进展进行综述。
【Abstract】 Uncaria genus( Rubiaceae) contains 34 species all over the world,of which 11 species and one variant are present in China. Five species,namely U. rhynchophylla,U. macrophylla,U. hirsuta,U. sinensis and U. sessilifructus,are documented in Chinese Pharmacopoeia as the raw materials of Uncariae Ramulus Cum Uncis. Indole alkaloids are the characteristic constituents of Uncaria plants,in addition to triterpenes,lignans and flavones. This paper reviews the progress of indole alkaloids and their distribution within the five Uncaria species documented in Chinese Pharmacopoeia for better understanding the active constituents of Uncariae Ramulus Cum Uncis.
【Key words】 Uncariae Ramulus Cum Uncis; indole alkaloids; chemical constituents; Uncaria;
- 【文献出处】 中国中药杂志 ,China Journal of Chinese Materia Medica , 编辑部邮箱 ,2019年04期
- 【分类号】R284
- 【网络出版时间】2018-11-22 15:46
- 【被引频次】9
- 【下载频次】751