【摘要】 奇异变形杆菌是革兰阴性细菌,在自然界中广泛存在,具有特殊的群集运动能力,与临床关系密切,可在膀胱和肾脏中形成结石,在尿道留置管外表面、内腔中形成结晶生物膜,是引起复杂尿路感染的主要病原体,主要的毒力因子包括菌毛、黏附素、尿素酶、溶血素、金属摄取和免疫逃避等。综述了近年来有关奇异变形杆菌毒力因子的研究,为相关研究提供参考。更多还原

【Abstract】 Proteus mirabilis is a Gram-negative bacterium with a special assembly moving ability, and widely exists in the natural environment. It has a close relationship with the clinic such as its extraordinary ability to cause complicated urinary tract infections(UTI). Some stones can be shaped by Proteus mirabilis in bladder and kidney and form a crystalline biofilm on the surface outer and inner cavity of the urethral indwelling catheter, it is the main pathogen causing complex urinary tract infections. The main virulence factors include fimbrae or pilus, adhesin, urease, hemolysin, metals intake and immune escape and so on. This article reviews some studies in virulence factors of Proteus mirabilis, aiming to deepen the understanding of the microorganism and provide reference for the subsequent studies to come.更多还原