【摘要】 非洲猪瘟(African swine fever,ASF)是由非洲猪瘟病毒(African swine fever virus,ASFV)引起的一种急性、烈性、出血性的猪传染性疫病,给疫情发生国家(地区)的养猪业带来严重的经济损失。ASFV作为双股DNA病毒,含有150-167个开放阅读框(ORFs),编码200余种蛋白质,其中结构蛋白约50种。结构蛋白作为病毒颗粒的主要组分,在病毒吸附、侵入和复制等感染过程中起着重要作用。综述了ASFV结构蛋白在病毒感染中的作用,以期为ASFV结构蛋白的进一步研究提供参考。更多还原

【Abstract】 African swine fever(ASF)is an acute,lethal,and hemorrhagic porcine infectious disease caused by African swine fever virus(ASFV)which has been caused serious economic losses to the pig industry. ASFV is a double-stranded DNA virus. The viral genome contains between 150 and 167 open reading frames(ORFs),and encodes for more 200 proteins,around 50 of them are structural proteins.The structural proteins service as the major composition of viral particles,and play important roles in the assembly of virions,viral adsorption,entry and replication. This paper reviews the roles of ASFV structural proteins in viral infection,and provides guidelines for further studies in the structural proteins of ASFV.更多还原