【摘要】 为揭示水鬼蕉生物碱（AHL）对HepG-2细胞作用,采用FITC-Annexin V/PI双染色法检测AHL对HepG-2细胞凋亡的影响,并检测了AHL对HepG-2细胞内Ca²⁺浓度、活性氧（ROS）、pH的影响。结果表明:AHL可以通过细胞内ROS、Ca²⁺、pH三者间相互作用而诱导细胞凋亡。更多还原

【Abstract】 In order to reveal the effect of alkaloids of Amaryllidaceae plant Hymenocallis littoralis（AHL）on HepG-2 cells,FITC-Annexin V/PI double staining was used to detect the effect of AHL on apoptosis of HepG-2 cells and on Ca²⁺ concentration,reactive oxygen species（ROS）and pH in HepG-2 cells.The results show that:AHL could induce apoptosis through the interaction of ROS,Ca²⁺,and pH in cells.更多还原