【摘要】 目的通过对攀枝花地区2 876例育龄期妇女的TORCH检测结果进行分析,了解该地区育龄期妇女TORCH的感染现状及流行特点。方法选取2017年1月至2018年12月在该院进行孕前筛查和早孕期检测的妇女2 876例,检测其血清TORCH IgM和IgG抗体,并对检测结果进行分析。结果在2 876例调查人群中,4种病原体的IgM抗体检出率从高到低依次为人抗单纯疱疹Ⅰ/Ⅱ型(anti-HSVⅠ/Ⅱ)IgM(2.23%)、人巨细胞病毒(CMV)IgM(0.83%)、人抗风疹病毒(anti-RV)IgM(0.35%)、人抗弓形虫(anti-TOX)IgM(0.10%);IgG抗体检出率从高到低分别为anti-CMV IgG(95.79%)、anti-HSVⅠ/ⅡIgG(90.82%)、antiRV IgG(90.16%)、anti-HSVⅡIgG(14.64%)、anti-TOX IgG(7.68%)。对检出率最高的anti-HSVⅠ/ⅡIgM进行季节和年龄组分析,发现秋季最容易发生感染,其次是春季,检出率为3.30%和2.37%;在年龄组比较中,以≥35岁组anti-HSVⅠ/ⅡIgM检出率最高(2.70%),但两个年龄组间差异无统计学意义(χ2=0.39,P=0.530)。比较13个地区TORCH活动性感染现状,各地区间有较大差异,以HSVⅠ/Ⅱ型差异最大;攀枝花地区的TORCH活动性感染率在13个地区中处于较低水平。结论攀枝花地区4种病原体的活动性感染率中HSVⅠ/Ⅱ型最高,TOX、RV和CMV较低。既往感染以CMV、HSVⅠ型及RV感染为主,TOX和HSVⅡ型较低。HSVⅠ/Ⅱ型感染有一定的季节性,秋、春季节高发;各年龄组差异无统计学意义。多个地区比较可见TORCH感染率受地域的影响较大,特别是HSVⅠ/Ⅱ型感染;攀枝花地区TORCH感染率处于较低水平,但孕期筛查仍有必要。更多还原

【Abstract】 Objective To investigate the prevalence of TORCH among 2 876 women of childbearing age in Panzhihua area.Methods A total of 2 876 women who underwent prenatal screening and early pregnancy testing in Panzhihua Central Hospital from January 2017 to December 2018 were selected to detect serum TORCH IgM and IgG antibodies,and the results were analyzed.Results The detection rates of IgM antibodies against 4 pathogens were anti-HSVⅠ/ⅡIgM(2.23%),anti-CMV IgM(0.83%),anti-RV IgM(0.35%)and anti-TOX IgM(0.10%)from high to low in 2 876 investigated population.The detection rates of IgG antibodies from high to low were anti-CMV IgG(95.79%),anti-HSVⅠ/ⅡIgG(90.82%),anti-RV IgG(90.16%),anti-HSV IgG(14.64%),anti-TOX IgG(7.68%).The highest detection rate of anti-HSVⅠ/Ⅱ IgM was found in autumn,followed by spring,with the detection rate of 3.30% and 2.37%.In the age group comparison,the highest detection rate of anti-HSVⅠ/ⅡIgM was found in the group over 35 years old(2.70%),but there was no significant difference between the two age groups(χ2=0.39,P=0.530).Compared with the current situation of active TORCH infection in 13 regions,there were significant differences among regions,with HSVⅠ/Ⅱtype being the most significant;the active TORCH infection rate in Panzhihua region was at a low level in 13 regions.Conclusion Among the four pathogens in Panzhihua area,HSVⅠ/Ⅱis the highest,while TOX,RV and CMV are lower.Previous infections were mainly CMV,HSV typeⅠ and RV,while TOX and HSV Ⅱ were lower.HSV Ⅰ/Ⅱinfection is seasonal with high incidence in autumn and spring,and there is no significant difference among age groups.The infection rate of TORCH in Panzhihua is relatively low,but screening during pregnancy is still necessary.更多还原