【摘要】 探讨太极拳健康干预对不同性别2型糖尿病患者治疗效果的差异性.招募2型糖尿病患者40例,其中男20例,女20例,均进行太极拳练习8周,每周5d,每天2次,每次60min.主要疗效指标包括空腹血糖(FBG)、餐后2h血糖(2hPBG)、糖化血红蛋白(HbA1c)、空腹胰岛素水平(FINS)、胰岛素抵抗(HOMA-IR)以及胰岛素敏感性(ISI);次要疗效指标包括高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、甘油三脂(TG)、总胆固醇(TC)、体质量指数(BMI)、血压(BP)、生活品质(GQOL-74).干预8周后,各项指标变化为:糖代谢指标,男女2组FBG、HbA1c以及HOMA-IR均非常显著性下降(P<0.01),2hPBG均显著性下降(P<0.05),但FBG及2hPBG下降幅度男性组显著性大于女性组(P<0.05),ISI均非常显著性升高(P<0.01);脂代谢指标,男女2组TG及BMI均非常显著性下降(P<0.01),其他指标差异无显著性(P>0.05);生活品质,男女2组心理功能均得到显著性提高(P<0.05),男性组躯体功能的改善显著性高于女性组(P<0.05),女性组社会功能的改善显著性高于男性组(P<0.05).8周太极拳练习作为辅助治疗手段,可以改善T2DM患者糖脂代谢水平以及提高其生活品质,其中男性组治疗效果优于女性组,其机制值得进一步研究.更多还原

【Abstract】 The effect of Tai Chi health intervention on the treatment effects of patients with type 2 diabetes was examined.A total of 40 type 2 diabetes patients were recruited,20 patients for each sex.All patients did Tai Chi exercises for 8 weeks,5 days a week,twice a day each session lasting for 60 min.Main clinical parameters examined were fasting blood glucose(FBG),2-hour postmeal blood glucose(2 hPBG),glycosylated hemoglobin(HbA1 c),fasting insulin level(FINS),insulin resistance(HOMA-IR)and insulin-sensitive(ISI)Other parameters examined were high density lipoprotein(HDL),low density lipoprotein(LDL),triglyceride(TG),total cholesterol(TC),body mass index(BMI),blood pressure(BP)and quality of life(GQOL-74).After 8 weeks of Tai Chi intervention,FBG,HbA1 cand HOMA-IR decreased significantly and 2 hPBG decreased significantly in both sex,but decrease in FBG and 2 hPBG in men was significantly higher than in women(P<0.05).ISI significantly increased(P<0.01).After 8 weeks of intervention,TG and BMI in both groups decreased significantly(P<0.01),but no significant difference was found between men and women in other indexes.After 8 weeks of intervention,the psychological function of both groups significantly improved(P<0.05),improvement in physical function in men was significantly higher than that in women(P<0.05).Improvement in social function in women was significantly higher than in men(P<0.05).It is concluded that8-week Tai Chi exercise improved glycolipid metabolism in patients with T2 DM and improved quality of life in patients with T2 DM The treatment effect in men was superior to women,the mechanism for this difference is worthy of further study.更多还原