【摘要】 为了探讨藏山羊(Capra hircus)与藏绵羊(Ovis aries)在高原低氧环境中肺组织结构的差异,采用Gomori醛品红染色及H.E染色对藏山羊和藏绵羊肺组织进行对比研究。结果表明,藏山羊与藏绵羊肺被膜厚度无显著差异(P> 0.05),但肺被膜中弹力纤维藏山羊显著多于藏绵羊(P <0.05)。肺泡面积藏山羊与藏绵羊无显著差异(P> 0.05),但肺泡隔宽度和肺泡隔中毛细血管的数量藏山羊显著高于藏绵羊(P <0.05)。肺细支气管黏膜皱襞厚度藏山羊与藏绵羊无显著差异(P> 0.05),但细支气管平滑肌厚度藏山羊显著高于藏绵羊,细支气管黏膜上皮1mm~2中杯状细胞数量藏山羊显著高于藏绵羊(P<0.05)。外径小于100μm的肺微动脉中,藏山羊血管平滑肌占外径百分比显著高于藏绵羊(P <0.05),而当外径大于100μm时,两者间差异不显著(P> 0.05)。更多还原

【Abstract】 The Gomori and H.E staining were used to explore the difference in lung microstructure between Tibetan goat(Capra hircus) and Tibetan sheep(Ovis aries). The results showed that there was no significant difference in lung capsule thickness between these two species(P > 0.05), but the number of elastic fibers in Tibetan goat lung capsule was more than that in Tibetan sheep(P < 0.05)(Fig.1 and Table 1). There was no significant difference in alveolar area(P > 0.05), but the alveolar septum of Tibetan goat was significantly wider with much more capillaries than that of Tibetan sheep(P < 0.05)(Table 2). There was no significant difference in the thickness of bronchioles plica, but the bronchiole smooth muscle of Tibetan goat was significantly thicker than that of Tibetan sheep(P < 0.05)(Fig.2 and Table 3). The average number of goblet cells in the bronchioles mucosa epithelium of Tibetan goat was significantly more than that in Tibetan sheep(P < 0.05)(Table 3). In addition, the percentage of vascular smooth muscle in the pulmonary arteriole with diameter less than 100 μm was significantly higher in Tibetan goat than that in Tibetan sheep(P < 0.05), while the difference was not significant when the pulmonary arteriole diameter was greater than 100 μm(P > 0.05)( Table 4).更多还原