【作者】 傅先水；

【导师】 董宝玮；

【作者基本信息】 中国人民解放军军医进修学院 ， 影像医学， 2002， 博士

【摘要】 目的：对一体化三维超声成像进行实验研究及临床应用研究。材料和方法：对活体新西兰白兔肝脏VX2肿瘤进行三维超声成像与标本对照实验研究；三维超声表面成像观察人体胆囊、膀胱内病变，及肝脏和肠管的三维立体形态；三维超声透视成像最小回声模式，观察肝内血管及扩张的胆管的立体形态，及其在三维空间内的毗邻关系；三维超声透视成像X线模式及混合回声模式，结合交互式人工勾边的数据分割方法，观察以肝脏为代表的实性脏器内实性病变的三维成像效果，并与术后标本对照。采用三维超声断面投影冠状面重建技术，显示人体内多种目标体的冠状面及其在立体数据盒内的坐标位置。对离体猪肝和猪肾，及人体内肝肾囊肿，进行三维超声容积测定的精度的研究。结果：对实验动物和人体内肝脏肿瘤的三维超声成像结果与术后标本吻合；三维超声成像可显示人体内目标的整体形态及毗邻关系，显示肝脏肿瘤的包膜的形态特征和镶嵌样结构、卫星结节的数目及分布；冠状面重建可大大弥补二维超声扫查的局限性；离体猪肾容 解放军军医进修学院 博士学位论文 积测定三维和二维超声误差分别为3．97士4刀0％和18．88土 9．95WP功刀1），临床肝肾囊肿容积测定三维和二维误差分别为4．29士 3．62％禾14．94士11．82％（V0．of）．结论：三维超声可弥补二维超声的 许多局限性，具有广泛临床应用价值。更多还原

【Abstract】 Objective To evaluate the significance of experimental study and clinical application of integrated three-dimensional ultrasound(3-d US). Material and Methods VX2 liver tumors of the New Zealand white rabbits in vivo were observed with 3-d ultrasound imaging, which were compared with specimens. Surface fitting display pattern of 3-d US were used to observe the whole anatomic features of lesions in gallbladder ,bladder, and the surface contour of liver and intestines of human being. Transparent display pattern of 3-d us imaging were used to observe the solid lesions in solid organs. Volume measurements of objective with different shapes in vitro and in vivo using 2-d us and 3-d us were validated and compared. Results: The whole anatomic features and relationships in three-dimensional space of different objects can be observed satisfactorily using 3-d us imaging, which were superior obviously to 2-d us imaging .The errors of volume measurements Of 3-d US were statistically less than that of 2-d US. Conclusion: Our results show that 3-d US imaging and 3-d US volume measurements have anextensive clinical applications.更多还原