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中国妇女绝经过渡期特征研究

Investigation of Characteristics of Chinese Women During Menopausal Transition Period

【作者】 王赵

【导师】 郁琦;

【作者基本信息】 北京协和医学院 , 临床医学, 2009, 博士

【摘要】 目的了解中国妇女在绝经过渡期的特征。方法对就诊更年期门诊的妇女进行关于绝经过渡期的问卷调查。建立数据库,应用SPSS13.0软件进行统计分析。结果1850名妇女完成调查,平均绝经年龄为49.6岁,进入绝经过渡期的平均年龄为46.22岁,出现绝经过渡期症状的平均年龄46.28岁。前5位症状依次为失眠(60%)、潮热出汗(51%)、感觉异常及耳鸣(45%)、骨关节肌肉痛(18%)以及疲乏无力(16%)。症状随年龄增加加重:从事家务工作与离退休妇女症状相对较重,有慢性病或有重大手术史等应激源的妇女症状较重;.激素治疗能有效改善更年期症状。结论对绝经过渡期女性特征的研究有助于完善绝经过渡期的分期研究;中国妇女绝经过渡期平均约持续3.4年,绝经过渡期开始的年龄与更年期症状开始发生的年龄基本吻合;年龄、月经状况、职业以及有无应急源可能与更年期症状有相关性。激素补充治疗可以有效缓解更年期症状。

【Abstract】 Objective:To investigate the characteristics of Chinese women during menopausal transition.Methods:Investigation was conducted with a questionnaire about menopausal transition composed by general conditions and Kupperman Menopause Index (KMI). All of the parameters were input into a database and analyzed by SPSS.Results:A total of1850women were interviewed. The average ages of natural menopause, entering menopause transition and on setting of menopausal symptoms were49.60,46.22and46.28years old, respectively. The five most frequent symptoms were insomnia (60%), hot flash or sweating (51%), paraesthesia (45%), aching in muscles and joint s (18%), worn out (16%). x2test revealed the association of aging, menopausal staging, occupation and stress with climacteric syndrome, and hormone treatment could improve climacteric syndrome.Conclusions:The investigation of the characteristics of women during menopause transition is helpful to improve the study on defining menopause transition. The average duration of menopausal transition is about3.4years. The age of on setting menopausal symptoms is parallel with the age of entering menopausal transition. Climacteric symptoms were common but mild in Chinese women during menopausal transition. Aging, menopausal staging, occupation and stress were related with climacteric syndrome, and hormone treatment could improve climacteric syndrome.

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