【摘要】 由于在人类医疗保健与集约化禽畜和水产养殖中的大量使用,痕量水平的喹诺酮类抗生素在水体、土壤及沉积物中广泛出现.因此,使用灵敏度高、选择性强的分析方法来检测环境中的痕量喹诺酮类抗生素,对了解其潜在的环境风险极为重要.本文综述了水体、土壤及沉积物样品中喹诺酮类抗生素萃取、富集与检测方法的最新进展.固相萃取(solid phase extraction,SPE)和超声/微波辅助萃取联合SPE分别是萃取和富集液相和固相(土壤和沉积物)样品中喹诺酮类抗生素最成熟可靠的方法.液相色谱-荧光检测联用和液相色谱-串联质谱联用技术是使用最为广泛的常规分析方法.此外,近年发展的免疫测定、生物传感器与电化学方法有望在筛检方面替代昂贵的仪器分析,尤其在现场实时监测领域具有较好的应用前景.更多还原

【Abstract】 Due to their heavy use in human health care and industrial food animal production,quinolones occur widely in surface water,soils,and sediments. Development of highly sensitive and selective analytical techniques for the detection of quinolones,often at trace levels,in environmental matrices is necessary to understand their risk to the environment. This review summarizes the recent development in sample pretreatment and determination of quinolone residues in aqueous samples,soils and sediments. Despite the recent development of novel extraction and pre-concentration methods,solid phase extraction( SPE), ultrasound-assisted extraction or microwave-assisted extraction followed by SPE are the most developede and reliable methods for the extraction and enrichment of quinolones in aqueous and solid samples, respectively. Liquid chromatographyfluorescence and liquid chromatography-triple quadrupole tandem mass spectrometry are widely used for the routine analyses of quinolones,while novel immunoassays,biosensors and electrochemical methods show promises as alternatives to the expensive instrumental analyses in screening,particularly for on-site real-time monitoring of these pollutants.更多还原