【摘要】 目的 对比分析人工流产术后采用短效口服避孕药以及单纯雌激素治疗对其子宫内膜产生的影响。方法 80例行人工流产术患者,以数字奇偶法分为参照组和研究组,每组40例。参照组患者术后当天选择单纯雌激素治疗,研究组患者术后当天选择短效口服避孕药治疗。比较两组患者治疗前后月经症状量表(MDQ)评分、子宫内膜厚度、雌激素[雌二醇(E2)、促卵泡生成素(FSH)以及促黄体生成素(LH)]水平及术后出血量、月经复潮时间、阴道出血持续时间、并发症(月经不调、盆腔感染、宫颈粘连、宫腔积液)发生情况。结果 治疗后,研究组患者MDQ评分(17.32±3.26)分低于参照组的(21.46±3.55)分,子宫内膜厚度(6.26±0.49)mm厚于参照组的(4.85±0.29)mm,差异具有统计学意义(P<0.05)。研究组患者术后出血量(52.13±10.92)ml少于参照组的(62.83±12.69)ml,月经复潮时间(28.52±4.55)d、阴道出血持续时间(5.03±1.42)d短于参照组的(36.85±5.29)、(8.69±2.55)d,差异具有统计学意义(P<0.05)。研究组患者并发症发生率为7.50%,低于参照组的30.00%,差异具有统计学意义(P<0.05)。治疗后,研究组患者E2、FSH及LH水平分别为(54.75±6.75)pg/ml、(11.51±3.71)U/L、(9.36±1.59)U/L,高于参照组的(50.52±7.69)pg/ml、(9.05±2.26)U/L、(8.63±1.61)U/L,差异具有统计学意义(P<0.05)。结论 与单纯雌激素治疗比较,临床对患者于人工流产术后当天选择短效口服避孕药治疗,可显著减少术后出血量,有效增加子宫内膜厚度,降低并发症发生率,对患者雌激素水平以及月经周期的尽快恢复发挥明显的促进作用。更多还原

【Abstract】 Objective To comparatively analyze the effects of short-acting oral contraceptives and estrogen therapy on endometrium after induced abortion. Methods A total of 80 patients undergoing induced abortion were divided into reference group and study group by digital parity method, with 40 cases in each group.The reference group was treated with estrogen alone on the day after surgery, and the study group was treated with short-acting oral contraceptives on the day after surgery. Both groups were compared in terms of menstrual distress questionnaire(MDQ) score, endometrial thickness, estrogen [estradiol(E2), follicle-stimulating hormone(FSH)and luteinizing hormone(LH)] levels before and after treatment, postoperative blood loss, time to return of menses,duration of vaginal bleeding, and occurrence of complications(irregular menses, pelvic infection, cervical adhesion,uterine effusion). Results After treatment, the MDQ score of(17.32±3.26) points in the study group was lower than that of(21.46±3.55) points in the reference group, and the endometrial thickness of(6.26±0.49) mm was thicker than that of(4.85±0.29) mm in the reference group. The differences were statistically significant(P<0.05).The postoperative blood loss of(52.13±10.92) ml in the study group was less than that of(62.83±12.69) ml in the reference group; the time to return of menses of(28.52±4.55) d and the duration of vaginal bleeding of(5.03±1.42) d in the study group were shorter than those of(36.85±5.29) and(8.69±2.55) d in the reference group; the differences were statistically significant(P<0.05). The incidence of complications in the study group was 7.50%,which was lower than that of 30.00%in the reference group, and the difference was statistically significant(P<0.05).After treatment, E2, FSH and LH levels were(54.75±6.75) pg/ml,(11.51±3.71) U/L, and(9.36±1.59) U/L in the study group, which were higher than those of(50.52±7.69) pg/ml,(9.05±2.26) U/L, and(8.63±1.61) U/L in the reference group, and the differences were statistically significant(P<0.05). Conclusion Compared with estrogen therapy alone, short-acting oral contraceptives on the day after induced abortion can significantly reduce postoperative blood loss, effectively increase endometrial thickness, reduce the incidence of complications, and significantly promote the estrogen level of patients and the recovery of menstrual cycle as soon as possible.更多还原