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颈椎术后C5麻痹病因分析及临床干预

Cause analysis and clinical intervention of C5 palsy after cervical surgery

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【作者】 徐晨霈周铭杰陈楚翔王洪立蒋苏

【Author】 XU Chenpei;ZHOU Mingjie;CHEN Chuxiang;WANG Hongli;JIANG Su;Department of Hand Surgery,Huashan Hospital,Fudan University;National Health Commission Key Laboratory of Hand Reconstruction;Shanghai Key Laboratory of Peripheral Nerve and Microsurgery;National Clinical Research Center for Aging and Medicine,Huashan Hospital,Fudan University;Institute of Hand Surgery;Institute of Hand Surgery,Fudan University;Department of Orthopedics,Huashan Hospital,Fudan University;Spinal Surgery Center,Fudan University;

【通讯作者】 蒋苏;

【机构】 复旦大学附属华山医院手外科国家卫生健康委员会手功能重建重点实验室上海市周围神经显微外科重点实验室复旦大学附属华山医院国家老年疾病临床医学研究中心上海市手外科研究所复旦大学手外科研究所复旦大学附属华山医院骨科复旦大学脊柱外科中心

【摘要】 目的 综述颈椎术后C5麻痹(C5 palsy,C5P)研究进展,为临床治疗C5P患者提供参考。方法 广泛查阅国内外颈椎术后C5P相关文献,系统性阐述C5P发病机制、危险因素、临床表现及诊断、预防、治疗措施新进展。结果 C5P为颈椎术后出现的C5神经支配区肌肉无力,表现为肩外展、屈肘受限,发生率>5%,可能由节段性脊髓损伤或神经根机械损伤导致。对于存在危险因素患者,术中仔细操作及采取预防性措施可减少术后C5P的发生。大部分患者经药物治疗、物理治疗等保守治疗后功能可恢复,6个月以上无明显好转者可予以手术干预,可选用椎间孔减压、神经移位等手术方案。结论 有关C5P发病机制及预防措施等已取得一定研究进展,但对于干预时机和手术方式仍需进一步研究。

【Abstract】 Objective To review the research progress of C5 palsy(C5P) after cervical surgery,providing new clinical intervention ideas for the C5P patients.Methods The relevant literature domestically and abroad was extensively consulted and the latest developments in the incidence,risk factors,manifestations and diagnosis,prevention,and intervention measures of C5P were systematically expounded.Results C5P is characterized by weakness in the C5 nerve innervation area after cervical decompression surgery,manifested as limited shoulder abduction and elbow flexion,with an incidence rate more than 5%,often caused by segmental spinal cord injury or mechanical injury to the nerve roots.For patients with risk factors,careful operation and preventive measures can reduce the incidence of C5P.Most of the patients can recover with conservative treatment such as drug therapy and physical therapy,while those without significant improvement after 6 months of treatment may require surgical intervention such as foraminal decompression and nerve displacement.Conclusion Currently,there has been some advancement in the etiology and intervention of C5P.Nevertheless,further research is imperative to assess the timing of intervention and surgical protocol.

【关键词】 C5麻痹神经根损伤颈椎手术并发症
【Key words】 C5 palsynerve root injurycervical surgerycomplication
【基金】 国家自然科学基金资助项目(82072545);上海市科学技术委员会科技创新计划项目(22S31902100);科技创新2030-重大项目(2022ZD0208605、2022ZD0208600);上海市临床重点专科项目(shslczdzk05601);上海市周围神经与显微外科重点实验室项目(20DZ2270200)~~
  • 【文献出处】 中国修复重建外科杂志 ,Chinese Journal of Reparative and Reconstructive Surgery , 编辑部邮箱 ,2024年05期
  • 【分类号】R687.3
  • 【网络出版时间】2024-04-25 19:16:00
  • 【下载频次】65
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