Pd–Ni–P metallic glass nanoparticles for nonenzymatic glucose sensing

【摘要】 Metallic glass nanoparticles hold great promise as nonenzymatic glucose sensors due to their rich low-coordinated active sites and high biocompatibility. However,their non-periodic atomic structure and unclear structure-property relationship pose significant challenges for realizing and optimizing their sensing performance. In this work, Pd–Ni–P metallic glass nanoparticles with variable compositions were successfully prepared as nonenzymatic glucose sensors via a laser-evaporated inertgas condensation method. The electrochemical tests show that the sensor based on Pd_41.25Ni_41.25P_17.5nanoparticles shows a wide linear detection range（0.003–1.31m M）, high sensitivity(516 μA m M^-1cm^-2), and high stability（～97.8% current retention after 1000 cycles）. Local structural investigations using synchrotron pair distribution function and high-resolution microscopic techniques reveal a strong structural correlation within short-to medium-range orders in the Pd_41.25Ni_41.25P_17.5nanoparticles, which can be well retained after electrochemical cycling. These atomic-scale structural characteristics might be responsible for the high sensing performance. This study demonstrates the high applicability of Pd–Ni–P metallic glass nanoparticles as sensitive and stable non-enzymatic glucose sensors.更多还原

【Abstract】 Metallic glass nanoparticles hold great promise as nonenzymatic glucose sensors due to their rich low-coordinated active sites and high biocompatibility. However,their non-periodic atomic structure and unclear structure-property relationship pose significant challenges for realizing and optimizing their sensing performance. In this work, Pd–Ni–P metallic glass nanoparticles with variable compositions were successfully prepared as nonenzymatic glucose sensors via a laser-evaporated inertgas condensation method. The electrochemical tests show that the sensor based on Pd_41.25Ni_41.25P_17.5nanoparticles shows a wide linear detection range（0.003–1.31m M）, high sensitivity(516 μA m M^-1cm^-2), and high stability（～97.8% current retention after 1000 cycles）. Local structural investigations using synchrotron pair distribution function and high-resolution microscopic techniques reveal a strong structural correlation within short-to medium-range orders in the Pd_41.25Ni_41.25P_17.5nanoparticles, which can be well retained after electrochemical cycling. These atomic-scale structural characteristics might be responsible for the high sensing performance. This study demonstrates the high applicability of Pd–Ni–P metallic glass nanoparticles as sensitive and stable non-enzymatic glucose sensors.更多还原