【摘要】 目的 探讨枸橼酸氢钾钠对预防留置双J管术后尿路感染的影响。方法 选取2020年1—12月阳江市人民医院泌尿外三科接收的130例留置双J管患者为研究对象，采用随机数字表法分为对照组和观察组，每组各65例，其中观察组口服枸橼酸氢钾钠颗粒；对照组不服用药物。观察两组血尿指标、手术相关资料以及并发症发生率。结果 留置前两组血白细胞（WBC）、尿WBC、尿β2微球蛋白（β2-MG）、血降钙素原（PCT）指标比较，差异无统计学意义（P>0.05）。留置7d时，观察组血WBC、尿WBC、β2-MG、血降钙素原（PCT）改善情况均优于对照组，差异有统计学意义（P <0.05）。观察组留置双J管时间较长，结石排净时间、术后住院时间显著短于对照组，差异有统计学意义（P <0.05）。观察组并发症发生率低于对照组，差异有统计学意义（P <0.05）。结论 枸橼酸氢钾钠用于预防留置双J管术后尿路感染效果显著，能显著改善患者血、尿指标水平，改善患者手术结局，且能降低并发症发生率，安全可靠，值得推广。更多还原

【Abstract】 Objective To investigate the impacts of postoperative urinary tract infection of indwelling double J tube with potassium sodium hydrogen citrate. Methods A total of 130 patients who accepted indwelling double J tube in Department Ⅲ of Urinary Surgery of People’s Hospital of Yangjiang from January to December 2020were selected as the research subjects, and they were divided into the control group(n=65) and the observation group(n=65) according to the random number table method.In them, the observation group was orally administrated with potassium sodium hydrogen citrate granule, while the control group was not administrated with drugs. The hematuria indices, operation-related data and the incidence of complications were observed in the two groups. Results There were no statistically significant differences in white blood cell(WBC), urinary WBC, β2-microglobulin(β2-MG) and procalcitonin(PCT) between the two groups before indwelling(P > 0.05).After 7 days’ indwelling, the observation group’s improvements in WBC, urinary WBC, β2-MG and PCT were all superior to those of the control group, with statistically significant differences(P < 0.05). The time of indwelling double J tube was longer, while the stone removal time and postoperative hospitalization time in the observation group were remarkably shorter than those in the control group, with statistically significant differences(P < 0.05). The incidence of complications in the observation group was lower than that in the control group, with statistically significant difference(P < 0.05). Conclusion Potassium sodium hydrogen citrate used to prevent postoperative urinary tract infection of indwelling double J tube has significant efficacy. It can significantly improve the level of blood and urine indices of patients, improve the surgical outcome of patients,and reduce the incidence of complications. Therefore, it is safe and reliable and worthy of promotion.更多还原