【摘要】 生物标志物是指可以作为正常生理过程、病理过程或对反应指标进行客观测量的指标，具有非常广泛的用途，如疾病诊断、判断疾病分期、评价新药或新疗法的安全性与有效性等。创伤后癫痫(PTE)作为创伤性颅脑损伤(TBI)后最为严重的并发症已经严重影响到国民健康，理应得到所有人的重视。本文总结的PTE生物标志物包括血浆/血清和脑脊液分子生物标志物、影像学生物标志物和电生理生物标志物，以期更加完善关于PTE的科学研究，并为其客观评定提供思路。更多还原

【Abstract】 Biomarkers are indicators that can be used as objective measures of normal physiological processes, pathological processes, or indicators of response, and have a very wide range of uses, such as diagnosis, disease staging, evaluation of the safety and efficacy of new drugs or treatments and so on. Post-traumatic epilepsy(PTE), as the most serious complication after traumatic brain injury(TBI), has seriously affected human health and deserves everyone’s attention. The PTE biomarkers summarized in this paper include plasma/serum and cerebrospinal fluid molecular biomarkers, imaging biomarkers and electrophysiological biomarkers, in order to improve the scientific research on PTE and provide ideas for its objective evaluation.更多还原