【摘要】 目的探讨新生儿先天性心脏病(CHD)的临床特点,提高早期诊断率。方法对确诊为CHD的新生儿92例,对其临床资料进行回顾性分析。结果本组CHD资料室间隔缺损39例占42.39%、继发孔型房间隔缺损20例占21.71%、动脉导管未闭24例占26.09%、单纯心脏畸形68例占73.91%、复合心脏畸形24例(占26.11%)。与配对组比较有家族史及合并其他遗传性疾病史因素χ2=5.74,P<0.05,有统计学意义,孕早期感染因素χ2=5.88P<0.05有统计学意义,母亲职业(个体)χ2=4.47P<0.05,有统计学意义。临床表现:气促40例占43.48%、青紫25例27.17%、心脏杂音78例占84.78%、合并肺炎50例54.35%。结论新生儿CHD类型较多,临床表现复杂,复合心脏畸形死亡率高,对可疑的CHD新生儿应及时进行超声心动图检查,早期诊断和制定恰当的治疗方案。对有高危因素的孕妇应注意胎儿CHD筛查。更多还原

【Abstract】 Objective:To explore the clinical features of neonatal congenital heart disease and improve early diagnosis rate.Methods:To make a retrospective analysis on the clinical data of the neonates who have been diagnosed CHD(n=92).Rusults:Of all these CHD,ventricular septal defect is about 42.39%(n=39),ostium secundum defect is about 21.71%(n=20),patent ductus arteriosus is about 26.09%(n=24),pure cardiac malformation is about 73.91%(n=68),complex cardiac malformation is about 26.11%(n=24).Compared with the matched-pare group,the CHD group has the factors of family medical history and other genetic disease history(χ2=5.74,P<0.05),and the infection in the time of early pregnacy(χ2=5.88,P<0.05),and the job of mother(χ2=4.77,P<0.05),which all have statistical significance.Clinical manifestation:anhelation is about 43.48%(n=40,cyanochroia is about 27.17%(n=25),cardiac murmur is about 84.78%(n=78),pneumonia is about 54.35%(n=50).Conclusion:Neonatal congenital heart disease has many types,its clinical manifestation is complicated,and the complex cardiac malformation has high death rate.So the neonate who we think it is diagnosed CHD should have ultrasonic cardiogram,then the neonate can be diagnosed early and have proper treatment.The gravida who is in high dangerous factors should have fetus CHD screening.更多还原