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轮状病毒检测在儿童病毒性肠炎临床诊断中的价值及意义

The clinical diagnostic value and significance of rotavirus detection in children’s viral enteritis

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【作者】 苗丽燕曲政海韩征利

【Author】 MIAO Li-yan1,2,QU Zheng-hai1,HAN Zheng-li2(1.Department of pediatrics of the affiliated hospital of Qingdao medical college,Qingdao university,Shandong 266003,China; 2.Department of pediatrics,Linzi people’s hospital of Zibo,Shandong255400,China)

【机构】 青岛大学医学院附属医院山东省临淄区人民医院儿科

【摘要】 目的:探讨轮状病毒检测在儿童病毒性肠炎临床诊断中的价值及意义。方法:应用胶体金方法对149例病毒性肠炎患儿粪便进行轮状病毒检测,并对其临床分型、治疗转归进行分析。结果:患病儿童年龄3个月至4岁1个月,平均年龄(13.9±9.6)月,149例患儿中,60例轮状病毒检测阳性,其中CK-MB升高23例(38.3%),ALT升高27例(45.0%);89例轮状病毒检测阴性,其中CK-MB升高18例(20.2%),ALT升高15例(16.9%),差异皆具有统计学意义(P<0.05)。在应用利巴韦林、热毒宁注射液治疗及对部分患儿加用丙种球蛋白,改用腹泻奶粉喂养后均获痊愈。结论:轮状病毒检测对于儿童病毒性肠炎临床分型及诊断有一定指导价值。

【Abstract】 Objective:To explore the clinical diagnostic value and significance of rotavirus detection in Children’s viral enteritis.Methods:Stool samples from 149 infants with viral enteritis were detected by using the method of gold colloi,and to analyze the clinical classification and treatment outcome.Results: The age range of children with diarrhea were three months to forty-nine months,and the average age was(13.9±9.6)months.Among 149 samples,60 cases existed positive RV antigen,23 of which appeared the value rise of CK-MB(38.3%),27 of which appeared that of ALT(45.0%),89 cases existed negative RV antigen,18 of which appeared the value rise of CK-MB(20.2%),15 of which appeared that of ALT(16.9%).There were significant differences between both of them(P<0.05).All the cases were recovered by the combination therapy of ribavirin and Retuning injection,part of which immunoglobulin(IvIg) and diarrhea milk was added.Conclusions: Rotavirus detection for clinical classification and diagnosis of children viral enteritis had a certain reference value and significance.

  • 【文献出处】 中国民康医学 ,Medical Journal of Chinese People’s Health , 编辑部邮箱 ,2012年15期
  • 【分类号】R725.1
  • 【被引频次】2
  • 【下载频次】75
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