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不同年龄段突发性聋患者的临床特征分析

Clinical characteristics and prognostic factors of patients with sudden deafness in different age groups

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【作者】 许雯雯刘泓毅魏之涵濮彧邓洁龚学晨齐静怀郝学静王骁霍小秀郭睿

【Author】 XU Wenwen;LIU Hongyi;WEI Zhihan;PU Yu;DENG Jie;GONG Xuecheng;QI Jinghuai;HAO Xuejing;WANG Xiao;HUO Xiaoxiu;GUO Rui;Graduate School of Hebei North University;

【通讯作者】 郭睿;

【机构】 河北北方学院研究生院空军特色医学中心耳鼻咽喉头颈外科

【摘要】 目的探讨不同年龄段突发性聋患者的临床特征及影响患者治疗疗效的相关高危因素分析。方法回顾性分析2018年1月—2020年4月就诊于空军特色医学中心耳鼻咽喉头颈外科的突发性聋患者共151例,按WHO对年龄的划分标准划分为青年组、中年组和老年组共3组,同时筛选出可能影响突发性聋治疗效果的高危因素,包括性别、患耳情况、耳闷、耳鸣、眩晕、高血压、糖尿病、高血脂、吸烟、饮酒,将统计数据进行χ~2检验和多因素Logistic回归分析,分析不同年龄段突发性聋患者临床特征和影响突发性聋患者治疗疗效的的高危因素。结果单因素分析结果显示中年组合并高血脂发病率最高(17.9%);老年组合并高血压、糖尿病发病率最高(52.5%、42.5%);3组比较,青年组初始听力曲线以低频下降为主,治疗有效率最高(78.2%),差异均有统计学意义(P<0.05)。多因素分析结果显示,性别、高血压、糖尿病、高血脂均不是突发性聋患者预后不良的独立危险因素(P>0.05)。结论不同年龄段突发性聋患者临床特征不同,初始听力曲线类型对突发性聋患者预后有重要影响,临床上需采取个体化治疗措施,以提高治疗有效率。

【Abstract】 Objective To investigate the clinical characteristics of patients with sudden deafness in different age groups and to analyze the related risk factors which influence the therapeutic effect. Methods The clinical data on 151 cases of patients with sudden deafness was retrospectively analyzed who had been treated in our center between January 2018 and April 2020.According to the WHO classification standard, these patientswere divided into young,middle-aged and elderly groups. Related factors which might have influenced the effect of treatment were screened, including gender, ear stuffiness, tinnitus, vertigo, high blood pressure, type 2 diabetes, hyperlipidemia, smoking, and drinking. The chi-square test and multivariatelogistic regression analysis were conducted to analyze the clinical characteristics of patients and risk factors. Results Single factor analysis showed that the middle-agedgroup had the highest incidence of hyperlipidemia(17.9%), while the elderly group had the highest incidence of hypertension and diabetes mellitus (52.5% and 42.5%, respectively).The young group in which the symptoms were mainly low frequency decline had the highest total effective rate(78.2%), a nd t he d ifferences were statistically significant(P<0.05). The multivariate analysis showed that age, hypertension, diabetes mellitusand hyperlipidemia were not independent risk factors for poor prognosis in patients with sudden deafness(P>0.05). Conclusion Clinical characteristics vary between different age groups of patients with sudden deafness. The initial hearing curve has important influence on the prognosis of patients, so individualized treatment should be adopted to improve the efficiency.

【基金】 全军保健专项科研项目(16BJZ03)
  • 【文献出处】 空军医学杂志 ,Medical Journal of Air Force , 编辑部邮箱 ,2020年06期
  • 【分类号】R764.437
  • 【下载频次】117
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