【摘要】 目的 了解长沙市尖锐湿疣的流行趋势和特征，为制定防控策略提供科学依据。方法 从中国疾病预防控制信息系统中的传染病监测平台导出2013—2022年长沙市报告的尖锐湿疣病例资料，运用描述流行病学方法分析三间分布特征，主要统计指标为报告发病率、年均增幅和构成比，对发病趋势进行线性趋势卡方检验，检验水准α=0.05。结果 2013—2022年长沙市尖锐湿疣报告发病率总体呈下降趋势(χ²_趋势=30.68,P<0.001)，从2013年的20.36/10万下降至2022年的14.91/10万。两性发病率均呈下降趋势(男性χ²_趋势=33.54,P<0.001；女性χ²_趋势=4.33,P=0.037)。各年间尖锐湿疣的高发年龄段均为20～39岁性活跃人群，0～19岁和20～24岁组的发病率呈增长趋势(χ²_趋势=32.28,P<0.001；χ²_趋势=222.83,P<0.001)，而25～29岁、30～34岁、35～39岁、40～44岁、50～54岁、55～59岁和65～69岁年龄组呈下降趋势(χ²_趋势=103.54,P<0.001；χ²_趋势=51.19,P<0.001；χ²_趋势=17.92,P<0.001；χ²_趋势=16.32,P<0.001；χ²_趋势=14.93,P<0.001；χ²_趋势=7.66,P=0.006；χ²_趋势=17.72,P<0.001)。高发地区主要为浏阳市、宁乡市和雨花区。各职业人群中报告病例数占比最多的是农民（30.46%），其次为家务、家政及待业（28.50%）。结论 长沙市近10年的尖锐湿疣报告发病率总体呈下降趋势，但需警惕该病年轻化的趋势。应加强青少年的性病防控宣教，重点对高发地区和人群加大防控力度，进一步优化尖锐湿疣防控策略。更多还原

【Abstract】 Objective To investigate the epidemiological trends and characteristics of condyloma acuminatum in Changsha, to provide a scientific basis for developing preventive and control strategies.Methods A descriptive epidemiological study was conducted to analyze the cases of condyloma acuminatum reported in Changsha from 2013 to 2022, which was derived from the infectious disease monitoring platform in the China Disease Prevention and Control Information System. The main statistical indicators were reported incidence, annual growth rate and composition ratio. The linear trend Chi-square test was performed on the incidence trend,and the test level was α=0.05.Results The reported incidence of condyloma acuminatum in Changsha from 2013 to 2022 showed a downward trend (χ²_trend=30.68, P<0.001), decreased from 20.36/105in 2013 to 14.91/105in2022. The incidence of both sexes showed a downward trend(male χ²_trend=33.54,P<0.001,femaleχ²_trend=4.33,P=0.037). The high-risk age group of condyloma acuminatum in each year was the sexually active population aged 20-39 years old, and the incidence of condyloma acuminatum showed an increasing trend only in 0-19 years old group and 20-24 years old group (χ²_trend=32.28,P<0.001,χ²_trend=222.83,P<0.001),while the 25-29,30-34,35-39,40-44,50-54,55-59 and65-69 age groups showed a downward trend (χ²_trend=103.54,P<0.001；χ²_trend=51.19,P<0.001；χ²_trend=17.92,P<0.001；χ²_trend=16.32,P<0.001；χ²_trend=14.93,P<0.001；χ²_trend=7.66,P=0.006；χ²_trend=17.72,P<0.001). The high incidence areas were mainly Liuyang City,Ningxiang City and Yuhua District. Farmers（30.46%） and housework or unemployment（28.50%） accounted for the largest proportion of reported cases among all occupational groups. Conclusions The reported incidence of condyloma acuminatum in Changsha showed a downward trend in the past ten years,but it is necessary to be alert to the increasing trend in youth. Therefore, the prevention and control of sexually transmitted diseases in adolescents should be strengthened. Meanwhile, priority should be given to the areas and populations with high incidence of condyloma acuminatum in order to optimize the prevention and control strategies.更多还原