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转移因子混合液穴位注射联合氯雷他定口服对变应性鼻炎的治疗效果

Observing clinical efficacy of acupoint injection of mixture solution of transfer factor combined with oral loratadine in treating allergic rhinitis

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【作者】 侯珣瑞梁欣樊同涛徐明马亦飞李丽红

【Author】 HOU Xunrui;LIANG Xin;FAN Tongtao;XU Ming;MA Yifei;LI Lihong;Department of Acupuncture,the Affiliated Hospital of Guizhou Medical University;Department of Otorhinolaryngology Head and Neck Surgery,the Affiliated Hospital of Guizhou Medical University;

【通讯作者】 李丽红;

【机构】 贵州医科大学附属医院针灸科贵州医科大学附属医院耳鼻喉头颈外科

【摘要】 目的 观察转移因子混合液穴位注射联合氯雷他定口服治疗变应性鼻炎的临床疗效。方法 将40例变应性鼻炎患者随机分为对照组和观察组,对照组予氯雷他定口服治疗,观察组在此基础上加用转移因子混合液穴位注射治疗,对比2组患者治疗前、后症状体征总分、外周血嗜酸性粒细胞(EOS)计数、血清一氧化氮(NO)水平以及临床疗效。结果 治疗前,2组患者症状体征总分、EOS计数及NO水平比较,差异无统计学意义(P> 0.05);2组治疗后症状体征总分、EOS计数、NO水平均低于治疗前,差异有统计学意义(P<0.01),且观察组低于对照组,差异有统计学意义(P<0.05);观察组总有效率高于对照组,差异有统计学意义(P<0.05)。结论 与单用氯雷他定口服比较,转移因子混合液穴位注射联合氯雷他定口服治疗变应性鼻炎疗效更佳。

【Abstract】 Objective To observe the clinical efficacy of acupoint injection of mixture solution of transfer factor combined with oral loratadine in treating allergic rhinitis( AR).Methods Forty patients with AR were randomly divided into control and observation groups. Control group was given with oral loratadine, while observation group was treated with oral loratadine plus acupoint injection of mixture solution of transfer factor. Total score of symptoms and signs, peripheral blood eosinophil(EOS) count, serum nitric oxide(NO) level, and clinical efficacy were compared before and after treatment between two groups.Results Before treatment,the total score of symptoms and signs, EOS counts, and NO levels in two groups were no significant difference(P> 0. 05). The total scores of symptoms and signs, EOS counts, and NO levels in two groups were lower after treatment than those before treatment(P< 0. 01), and they were lower in observation group than in control group(P<0. 05). Total clinical efficacy rate was higher in observation group than that in control group(P<0. 05).Conclusion Acupoint injection of mixture solution of transfer factor combined with oral loratadine is more effective than oral loratadine alone in treating AR.

【基金】 贵州省中医药管理局中医药、民族医药科学技术研究课题(QZYY-2016-048)
  • 【文献出处】 贵州医科大学学报 ,Journal of Guizhou Medical University , 编辑部邮箱 ,2022年09期
  • 【分类号】R765.21
  • 【下载频次】31
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