【作者】 邓传超；

【导师】 朱瑛；

【作者基本信息】 云南中医学院 ， 中医儿科学（专业学位）， 2015， 硕士

【摘要】 目的:本课题通过对抗支颗粒治疗小儿肺炎支原体感染燥邪犯肺型的临床研究,客观、真实评估该方的临床疗效,以期为本方治疗本病提供科学的依据。方法:用数字随机分组法将符合本研究的患儿随机分为观察组和对照组,最终收集到符合本研究的患儿两组各30例。观察组口服抗支颗粒,对照组口服阿奇霉素颗粒(海口奇力制),两组均连续治疗14天,综合评价两组患儿服药后症状、体征及辅助检查的改善状况。结果:抗支颗粒能有效治疗肺炎支原体感染导致的咳嗽、咯痰、发热、鼻塞、流涕等症状,并在改善患儿食欲、大小便方面具有明显优势。①观察组总有效率为93.3%,对照组总有效率为83.3%,观察组总疗效优于对照组,差异有统计学意义(P<0.05);②观察组对咳嗽、发热、肺部听诊、大小便、食欲方面的疗效优于对照组,差异有统计学意义(P<0.05);③两组对咯痰、鼻塞、流涕、咽充血、扁桃体、胸片、血象方面的改善,两组疗效相当,差异无统计学意义(P>0.05);④对照组治疗后的发热、大小便评分和治疗前比较,差异均无统计学意义(P>0.05),说明对照组对这3项治疗不理想。对照组治疗后的食欲减退评分和治疗前比较有所上升,差异有统计学意义(P<0.05),说明对照组对改善食欲治疗效果不理想。两组患儿治疗期间均未发现不良反应。结论:通过对抗支颗粒治疗小儿肺炎支原体感染燥邪犯肺型咳嗽的临床研究,证明该方治疗小儿肺炎支原体感染燥邪犯肺型咳嗽疗效肯定,且无明显毒副作用,服用安全、方便,值得进一步推广应用于临床。更多还原

【Abstract】 Objective: This article through to kang Zhi, Drug Granules in the treatment of pediatric pneumonia mycoplasma infection dryness affecting lungs Clinical curative effect of observation and study, and discusses their mechanism of action, the curative effect of the party to make an objective evaluation, so as to provide scientific basis for clinical treatment of the disease.Methods: With digital random grouping will comply with the children of this study were randomly divided into observation group and control group, the ultimate collection in accordance with this study of children in the two groups 30 cases each.Observation group orally kang Zhi, Drug Granules, the control group oral azithromycin granules(Haikou Qili), two groups of treatment for 14 consecutive days, comprehensive evaluation of two groups of children with the improvement of the symptoms, signs and auxiliary examination after taking this medicine.Results: kang Zhi Drug Granules can effectively relieve or eliminate mycoplasma pneumoniae infection symptoms such as cough, sputum, and in regard to protect children taste, children improve diet, has obvious advantages in urine.The total effective rate was 93.3%(1) group, control group total effective rate was 83.3%, the difference was statistically significant(P < 0.05), the observation group total effectiveness is better than the control group;(2) the observation group in improving cough, fever, lung auscultation, urine, appetite is better than that in control group, the difference was statistically significant(P < 0.05);(3) group in improving cough up phlegm, stuffy nose, runny nose, pharynx hyperemia,tonsil,chest X-ray, blood picture on curative effect and the control group, there was no statistically significant difference(P > 0.05);(4) in the control group after treatment of fever, wears score compared with before treatment, there were no statistically significant difference(P > 0.05), and still can’t believe this three symptoms treatment is effective.The control group after treatment of anorexia score compared with before treatment has increased, the difference was statistically significant(P < 0.05), the control group to improve appetite treatment effect is not ideal.During the treatment, two groups of children with no adverse reaction occurred.Conclusion: By kang Zhi, Drug Granules in the treatment of pediatric pneumonia mycoplasma infection dryness affecting lungs of clinical research, proved that the party in the treatment of pediatric pneumonia mycoplasma infection dryness affecting lungs curative effect, and no obvious side effects, safe, convenient, worthy of clinical popularization and application.更多还原