【摘要】 目的探讨CT增强扫描非离子型碘对比剂不良反应及临床特点。方法选取我院行CT增强和血管CTA增强扫描46例碘对比剂不良反应患者临床资料,分析其原因及采取措施。结果 46例患者中,轻度不良反应占58.69%(27/46);中度不良反应占34.78%(16/46);重度不良反应占6.52%(3/46)。碘普罗胺不良反应的例数高于碘克沙醇与碘佛醇,组间比较差异具有统计学意义(P<0.05)。碘普罗胺急性不良反应的例数高于碘克沙醇与碘佛醇,组间比较差异具有统计学意义(P<0.05),而碘克沙醇迟发性过敏反应多见(P<0.05)。所有患者经休息,对症处理及抗过敏治疗,均治愈好转。结论为提高碘对比剂使用的安全性,应早预防及时进行临床干预,确保用药安全。更多还原

【Abstract】 Objective To investigate the adverse reactions and clinical characteristics of nonionic iodine contrast agents in CT patients. Methods The clinical data of 46 cases of adverse reactions to iodide contrast agents by CT enhancement and vascular CTA examination in Texas regional imaging center were collected to analyze the causes and takeing measures. Results There were 46 cases of iodine contrast agents with mild adverse reactions 58.69%(27/46). Moderate adverse reactions accounted for 34.78%(16/46). Severe adverse reactions accounted for 6.52%(3/46). The number of adverse reactions of ioprolamine was higher than that of iodixanol and iofol, and the difference between the two groups was statistically significant(P<0.05). The number of acute adverse reactions was higher than that of iodoproamine and iodoverol, and the difference between the two groups was statistically significant(P<0.05), while late allergic reactions of iodoprolol were more common(P<0.05). All patients were cured by rest, symptomatic treatment and antiallergic treatment. Conclusion In order to improve the safety of iodine contrast agent, the characteristics and clinical manifestations of adverse reactions of iodine contrast agent should be identified early, and timely intervention should be made to ensure the safety of drug use.更多还原