【摘要】 目的探讨不同血糖控制水平对ICU应激性高血糖(SHG)患者预后的影响。方法选取2013年5月至2016年12月该院ICU收治的危重SHG患者117例,采取常规胰岛素治疗,将117例患者分为研究组(76例)和对照组(41例),研究组患者血糖水平控制在6.1~8.0 mmol/L,对照组患者血糖水平控制在8.1~10.0 mmol/L。通过观察患者入院1、7、14 d的降钙素原、C-反应蛋白、白细胞水平,以及住院时间、肺部感染发生率、入院21 d内病死率等情况,评估两组患者的近期预后。结果研究组患者住院时间、肺部感染发生率、病死率均优于对照组,差异均有统计学意义(P<0.05);入院1、7、14 d,研究组患者降钙素原、C-反应蛋白、白细胞水平较对照组均有所降低,但差异无统计学意义(P>0.05)。结论控制血糖水平在6.1~8.0 mmol/L可有效改善ICU中SHG患者的预后,并可较好地控制机体的炎性反应。更多还原

【Abstract】 Objective To explore regular insulin therapy to control blood sugar in different levels on the prognosis of pa tients with stress hyperglycemia(SHG) in the ICU. Methods A total of 117 patients with severe SHG who were sent to ICU in the hospital from May 2013 to December 2016. Regular insulin therapy was taken,all patients were divided into research group(76 cases)and control group(41 cases). The blood glucose level was controlled at 6.1-8.0 mmol/L in the research group,which was controlled at 8.1—10.0 mmol/L in the control group. The hospitalized 1,7,14 d of calcitonin zymogen,C-reactive protein,white blood cell levels of the patients were observed,as well as the hospitalization time,pulmonary infection incidence,mortality of the hospitalized 21 d,to evaluate the recent prognosis of two groups. Results The hospitalized time,mortality,pulmonary infection incidence in the re search group were lower than those in the control group, the differences were statistically significant(P<0.05);compared with the control group,the calcitonin zymogen,C-reactive protein,white blood cell levels in the research group were reduced,but the differences were no statistically significant(P>0.05). Conclusion Controlling level of blood sugar at 6.1—8.0 mmol/L of ICU in the hospital can improve the prognosis of patients with SHG,and its a good way to control the body′s inflammatory response.更多还原