【摘要】 石骨症(osteopetrosis, OP)又名粉笔样骨、大理石骨病等，是一种罕见的、原因不明的因破骨细胞数量减少或功能异常的具有遗传倾向的代谢性骨病。临床表现复杂多样，影像学表现主要以全身骨密度广泛增高。本文报道一例石骨症伴下颌骨骨髓炎患者资料，复习既往文献，对该疾病的发病机制、临床分型及治疗作一概述，为以后临床治疗此类疾病提供参考。更多还原

【Abstract】 Osteopetrosis(OP), also known as chalk like bone disease or marble bone disease, is a rare and unexplained metabolic bone disease with genetic predisposition due to reduced osteoclast count or abnormal function. The clinical manifestations are complex and diverse, with imaging manifestations mainly characterized by widespread increase in bone density throughout the body. This article reports the data of a patient with osteopetrosis accompanied by mandibular osteomyelitis. Previous literature is reviewed to provide an overview of the pathogenesis, clinical classification, and treatment, providing reference for future clinical treatment of this disease.更多还原