节点文献

血液肿瘤精准诊治

Precision diagnosis and treatment for hematological malignancies

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 张曦

【Author】 ZHANG Xi;State Key Laboratory of Trauma and Chemical Poisoning,Medical Center of Hematology,Military Key Clinical Specialty, Chongqing Key Clinical Specialty, Chongqing Key Laboratory of Hematology and Microenvironment, Second Affiliated Hospital, Army Medical University (Third Military Medical University);Jinfeng Laboratory;

【通讯作者】 张曦;

【机构】 陆军军医大学(第三军医大学)第二附属医院血液病医学中心,全军临床重点专科,创伤与化学中毒全国重点实验室,重庆市临床重点专科,血液病与微环境重庆市重点实验室金凤实验室

【摘要】 目的 随着对血液肿瘤发病机制的深入研究,血液肿瘤的精准诊断和分层治疗逐年优化提升。近年来在人工智能的推动下,血液肿瘤诊断由人工化、经验化不断向智能化、信息化升级,在未来有望实现高效、高准确率的智能诊断;同时,小分子药物、抗体类药物、免疫细胞治疗及造血干细胞移植新疗法在不断完善,新药不断涌现,为血液肿瘤的治疗提供了更多选择。本文从血液肿瘤的精准/智能诊断、药物治疗和细胞治疗等3个方面探讨血液肿瘤的精准诊断与治疗。

【Abstract】 With the in-depth research on the pathogenesis of hematological malignancies,precision diagnosis and stratified treatment have been continuously enhanced and optimized over the years. In recent years,with the aid of artificial intelligence,the diagnosis of the malignancies has been upgraded from manual and empirical to intelligent and mechanized,and it is expected to realize intelligent diagnosis with high efficiency and high accuracy in the future. At the same time,the evolution of small molecule drugs,antibody drugs,immunotherapy and hematopoietic stem cell transplantation,and the emergence of new drugs expand the treatment options for hematological malignancies. In this article,we review the precision diagnosis and treatment of hematological tumors from 3 aspects: precision/intelligent diagnosis,medication,and cellular therapy.

【基金】 国家自然科学基金国际(地区)合作与交流项目(82020108004);重庆市自然科学基金创新群体科学基金(cstc2021jcyj-cxttX0001);陆军军医大学第二附属医院学科人才建设专项项目(2022XKRC001)~~
  • 【文献出处】 陆军军医大学学报 ,Journal of Army Medical University , 编辑部邮箱 ,2024年04期
  • 【分类号】R733
  • 【下载频次】366
节点文献中: 

本文链接的文献网络图示:

本文的引文网络