【摘要】 目的 观察上焦宣痹汤加减辅助治疗儿童急性鼻-鼻窦炎所致上气道咳嗽综合征湿热证的临床疗效。方法 选取2019年1月至2023年1月江西中医药大学第二附属医院儿科住院部就诊的急性鼻-鼻窦炎所致上气道咳嗽综合征湿热证患儿60例，采用随机数字表法分为治疗组和对照组，各30例。对照组给予西医对症治疗，治疗组在对照组治疗方法的基础上给予上焦宣痹汤加减治疗。2组均治疗2周后统计临床疗效，比较治疗前后咳嗽主观症状评分、视觉模拟量表（VAS）评分以及不良反应发生情况，随访3个月统计复发率。结果 治疗组总有效率为93.33%(28/30)，显著高于对照组的73.33%(22/30),2组比较，差异有统计学意义（P<0.05）。治疗前，2组VAS、咳嗽症状评分比较，差异无统计学意义（P>0.05），具有可比性；治疗后，2组上述评分较治疗前均降低，与同组治疗前比较，差异有统计学意义（P<0.05），且治疗组下降更显著（P<0.05）。对照组复发率为31.82%(7/22)，显著高于治疗组的7.14%(2/28),2组比较，差异有统计学意义（P<0.05）。对照组不良反应发生率为10.00%(3/30)，治疗组为13.33%(4/30),2组比较，差异无统计学意义（P>0.05）。结论上焦宣痹汤加减辅助治疗儿童急性鼻-鼻窦炎所致上气道咳嗽综合征湿热证疗效满意，可显著降低患儿咳嗽症状、VAS积分和复发率，且无明显不良反应，值得临床推广应用。更多还原

【Abstract】 ObjectiveTo observe the clinical efficacy of adjuvant therapy with modified Shangjiao Xuanbi Tang（上焦宣痹汤）in the treatment of upper airway cough syndrome of damp heat pattern caused by acute rhinosinusitis in children.MethodsA total of 60 pediatric patients with upper airway cough syndrome of damp heat pattern caused by acute rhinosinusitis admitted to pediatric inpatient department of No.2 Affiliated Hospital of Jiangxi University of Chinese Medicine from January 2019 to January 2023 were selected and divided into a treatment group and a control group using a random number table method,with 30 patients in each group. The control group received symptomatic Western medicine treatment,while the treatment group received modified Shangjiao Xuanbi Tang on the basis of the control group’s treatment. Clinical efficacy was evaluated,and subjective cough symptom scores,Visual Analog Scale(VAS)scores before and after treatment,adverse reactions,and recurrence rates were compared.ResultsThe total effective rate in the treatment group was 93.33%(28/30),significantly higher than that in the control group(73.33%,22/30). The difference between the two groups was statistically significant(P<0.05). Before treatment,there were no statistically significant differences in VAS scores and cough symptom scores between the two groups(P>0.05),indicating comparability. After treatment,both scores decreased significantly in both groups compared with those before treatment(P<0.05),with a more significant decrease observed in the treatment group(P<0.05). The recurrence rate in the control group was 31.82%(7/22),significantly higher than that in the treatment group(7.14%,2/28). The difference between the two groups was statistically significant(P<0.05). In the control group,with an adverse reaction rate of 10.00%(3/30). In the treatment group,with an adverse reaction rate of 13.33%(4/30). The difference between the two groups was not statistically significant(P>0.05).Conclusion Adjuvant therapy with modified Shangjiao Xuanbi Tang for upper airway cough syndrome of damp heat pattern caused by acute rhinosinusitis in children exhibits satisfactory efficacy,significantly reducing cough symptoms,VAS scores,and recurrence rates,with no significant adverse reactions. It is worthy of clinical promotion and application.更多还原